Varma Pavika, Zaniletti Isabella, Murthy Karna, Grover Theresa R, Hwang Sunah S, Bourque Stephanie L
Section of Neonatology, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
Children's Hospitals Neonatal Consortium, Overland Park, KS, USA.
J Perinatol. 2025 Apr 24. doi: 10.1038/s41372-025-02314-0.
Investigate demographic and clinical factors and inter-center variability associated with home NGT versus GT in preterm infants.
Retrospective cohort study of preterm infants in the Children's Hospitals Neonatal Database discharged home with a NGT or GT between 2015-2020. Multivariable logistic regression assessed the independent relationship between infant characteristics and feeding modality. Bivariate analysis evaluated inter-center variability.
3521 preterm infants discharged with tube feedings (NGT 39%; GT 61%). Hispanic infants (AOR 1.57, 95% CI 1.15, 2.14) and SGA infants (AOR 1.27, 95% CI 1.02, 1.6) were more likely to receive GT feedings. Privately insured infants had decreased likelihood of receiving GT (AOR 0.57, 95% CI 0.45, 0.72). Infants discharged with NGT had shorter hospital stays (70[34,111] vs. 86 [39,138] days, p < 0.01). Significant inter-center variability among sites exists.
Differences in tube feeding at discharge were noted by infant race and ethnicity, SGA status, and insurance type.
研究与早产儿家庭鼻胃管喂养（NGT）和胃造口术喂养（GT）相关的人口统计学和临床因素以及中心间变异性。
对2015 - 2020年间儿童医院新生儿数据库中出院回家时采用NGT或GT喂养的早产儿进行回顾性队列研究。多变量逻辑回归评估婴儿特征与喂养方式之间的独立关系。双变量分析评估中心间变异性。
3521名早产儿出院时采用管饲喂养（NGT占39%；GT占61%）。西班牙裔婴儿（调整后比值比[AOR]为1.57，95%置信区间[CI]为1.15，2.14）和小于胎龄儿（SGA）（AOR为1.27，95% CI为1.02，1.6）接受GT喂养的可能性更高。有私人保险的婴儿接受GT喂养的可能性降低（AOR为0.57，95% CI为0.45，0.72）。出院时采用NGT喂养的婴儿住院时间较短（70[34,111]天对86[39,138]天，p < 0.01）。各中心之间存在显著的中心间变异性。
出院时管饲喂养的差异在婴儿种族和民族、SGA状态以及保险类型方面有所体现。
