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后锯肌上肋间平面阻滞对乳腺癌手术患者术后镇痛的影响:一项随机对照试验。

Effects of serratus posterior superior intercostal plane block on postoperative analgesia in patients undergoing breast cancer surgery: a randomized controlled trial.

作者信息

Köksal Bengü G, Baytar Çağdaş, Bayraktar Emine, Balbaloğlu Hakan

机构信息

Department of Anesthesiology and Reanimation, Zonguldak Bülent Ecevit University Faculty of Medicine, Zonguldak, Turkey.

Department of General Surgery, Zonguldak Bülent Ecevit University Faculty of Medicine, Zonguldak, Turkey.

出版信息

BMC Anesthesiol. 2025 Apr 24;25(1):209. doi: 10.1186/s12871-025-03092-0.

Abstract

BACKGROUND

The serratus posterior superior intercostal plane block (SPSIPB) is a newly described truncal block. This study aimed to compare the effects of SPSIPB with conventional methods on postoperative opioid consumption and pain scores within 24 h postoperatively.

METHODS

This randomized controlled trial included 60 patients aged 18-65 years with an American Society of Anesthesiologists Physical Status of I-III. Patients were randomly assigned to either the SPSIPB or the control group. The primary outcome was cumulative opioid consumption within the first 24 h postoperatively. Secondary outcomes included resting and dynamic Numerical Rating Scale (NRS) pain scores, Quality of Recovery (QoR)-15 questionnaire scores, intraoperative remifentanil consumption, and the incidence of postoperative nausea and vomiting.

RESULTS

Total tramadol consumption was significantly lower in the SPSIPB group during the first 12 h and at the end of the 24th hour postoperatively compared with the control group (p < 0.05). The dynamic NRS score at 0 h postoperatively was lower in the SPSIPB group (p = 0.001), whereas no significant differences in NRS scores were observed at other time-points. The postoperative QoR-15 scores were significantly higher in the SPSIPB group compared with the control group. Furthermore, the SPSIPB group had significantly lower intraoperative remifentanil consumption (p = 0.003). Nausea and vomiting were more frequent at 12 and 24 h postoperatively in the control group compared with the SPSIPB group.

CONCLUSIONS

Serratus posterior superior intercostal plane block significantly reduced opioid use, and improved recovery quality after oncoplastic breast surgery.

TRIAL REGISTRATION

NCT06225908, registered at ClinicalTrials.gov.

摘要

背景

后锯肌上肋间平面阻滞(SPSIPB)是一种新描述的躯干阻滞。本研究旨在比较SPSIPB与传统方法对术后24小时内阿片类药物消耗量和疼痛评分的影响。

方法

这项随机对照试验纳入了60例年龄在18 - 65岁、美国麻醉医师协会身体状况分级为I - III级的患者。患者被随机分配到SPSIPB组或对照组。主要结局是术后首24小时内的累积阿片类药物消耗量。次要结局包括静息和动态数字评定量表(NRS)疼痛评分、恢复质量(QoR)- 15问卷评分、术中瑞芬太尼消耗量以及术后恶心呕吐的发生率。

结果

与对照组相比,SPSIPB组术后首12小时及术后24小时末的曲马多总消耗量显著更低(p < 0.05)。SPSIPB组术后0小时的动态NRS评分更低(p = 0.001),而在其他时间点NRS评分未观察到显著差异。SPSIPB组术后QoR - 15评分显著高于对照组。此外,SPSIPB组术中瑞芬太尼消耗量显著更低(p = 0.003)。与SPSIPB组相比,对照组术后12小时和24小时恶心呕吐更频繁。

结论

后锯肌上肋间平面阻滞显著减少了阿片类药物的使用,并改善了肿瘤整形乳房手术后的恢复质量。

试验注册

NCT06225908,在ClinicalTrials.gov注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38d8/12020093/2b2c81d8942b/12871_2025_3092_Fig1_HTML.jpg

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