Deptula Peter, McCullough Meghan, Brown Theodore, Singh Dylan, Tanabe Kylie, Tsai Eugene, Kulber David
From the Department of Orthopaedic Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Division of Plastic and Reconstructive Surgery, Stanford University, Stanford, CA.
Plast Reconstr Surg Glob Open. 2025 Apr 24;13(4):e6720. doi: 10.1097/GOX.0000000000006720. eCollection 2025 Apr.
Prior studies have shown that intra-articular injection of autologous fat may be a viable, less invasive approach for the treatment of carpometacarpal (CMC) joint arthritis, compared with trapeziecetomy. Small joint arthroscopy has also been found to be a useful tool in evaluation and treatment of arthritis. The authors present a treatment for CMC arthritis combining a minimally invasive approach for arthroscopic debridement with autologous fat grafting and platelet-rich plasma (PRP) injection.
Patients with Eaton stage II-IV CMC osteoarthritis underwent arthroscopic debridement and injection of autologous fat and PRP into the joint. Pre- and postoperative pain scores, functional outcomes, radiographic improvement in joint subluxation, patient satisfaction, and complications were evaluated.
Forty-eight thumb CMC joint arthroscopies with fat grafting and PRP were performed. No intraoperative or immediate postoperative complications were experienced. No patients required revision surgery. Average preoperative pain scores with activity improved from 8.9 ± 0.9 to 3.3 ± 2.2 ( < 0.0001) and at rest improved from 5.0 ± 2.5 to 1.0 ± 1.3 ( < 0.0001). MM overlap was used to measure radiographic subsidence. This improved from 4.4 ± 2.8 mm preoperatively to 6.8 ± 2.3 mm postoperatively, reflecting a relative improvement of 70% ( < 0.0042). High patient satisfaction was noted.
Treatment of the CMC joint using arthroscopic technique combined with autologous fat and PRP is effective in treating pain and joint subluxation. Additional prospective studies are underway for comparison to traditional arthroplasty techniques and to evaluate this technique's potential for other small joint pathology.
先前的研究表明,与大多角骨切除术相比,关节内注射自体脂肪可能是一种可行的、侵入性较小的治疗第一腕掌(CMC)关节关节炎的方法。小型关节镜检查也被发现是评估和治疗关节炎的一种有用工具。作者介绍了一种治疗CMC关节炎的方法,该方法将关节镜清创的微创方法与自体脂肪移植和富血小板血浆(PRP)注射相结合。
伊顿II-IV期CMC骨关节炎患者接受关节镜清创,并向关节内注射自体脂肪和PRP。评估术前和术后的疼痛评分、功能结果、关节半脱位的影像学改善、患者满意度和并发症。
对48例拇指CMC关节进行了脂肪移植和PRP的关节镜检查。未发生术中或术后即刻并发症。没有患者需要翻修手术。活动时平均术前疼痛评分从8.9±0.9改善至3.3±2.2(<0.0001),休息时从5.0±2.5改善至1.0±1.3(<0.0001)。用MM重叠来测量影像学下沉情况。这一数值从术前的4.4±2.8mm改善至术后的6.8±2.3mm,相对改善了70%(<0.0042)。患者满意度较高。
使用关节镜技术结合自体脂肪和PRP治疗CMC关节在治疗疼痛和关节半脱位方面是有效的。正在进行更多前瞻性研究,以与传统关节成形术技术进行比较,并评估该技术在其他小关节病变中的潜力。