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大梗死性缺血性卒中的血管内血栓切除术

Endovascular Thrombectomy for Ischemic Stroke With Large Infarct.

作者信息

Khan Faizan, Yogendrakumar Vignan, Menon Bijoy K

机构信息

Department of Clinical Neurosciences, Radiology and Community Health Sciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Alberta, Canada (F.K., B.K.M.).

Division of Neurology, The Ottawa Hospital and Ottawa Hospital Research Institute, University of Ottawa, Ontario, Canada (V.Y.).

出版信息

Stroke. 2025 Jun;56(6):1655-1658. doi: 10.1161/STROKEAHA.125.050897. Epub 2025 Apr 25.

Abstract

Endovascular thrombectomy (EVT) is a safe and effective treatment for acute ischemic stroke caused by large vessel occlusion. However, earlier randomized trials of endovascular thrombectomy did not include many patients with large infarctions, leading to their exclusion from this treatment. Recent randomized trials have shown that endovascular thrombectomy is superior to medical management alone in improving functional outcomes in ischemic stroke cases with large infarcts. This commentary provides an overview of these trials and discusses important considerations for implementing these results into clinical practice.

摘要

血管内血栓切除术(EVT)是治疗由大血管闭塞引起的急性缺血性卒中的一种安全有效的方法。然而,早期血管内血栓切除术的随机试验并未纳入许多大面积梗死患者,导致他们被排除在这种治疗之外。最近的随机试验表明,在改善大面积梗死的缺血性卒中病例的功能结局方面,血管内血栓切除术优于单纯药物治疗。本述评概述了这些试验,并讨论了将这些结果应用于临床实践的重要注意事项。

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