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本文引用的文献

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JAMA Health Forum. 2024 May 3;5(5):e240901. doi: 10.1001/jamahealthforum.2024.0901.
2
Attacks on Ukrainian healthcare facilities during the first year of the full-scale Russian invasion of Ukraine.在俄罗斯对乌克兰全面入侵的第一年里对乌克兰医疗设施的袭击。
Confl Health. 2023 Dec 8;17(1):57. doi: 10.1186/s13031-023-00557-2.
3
Russia's invasion of Ukraine: an attack on health.俄罗斯对乌克兰的入侵:对健康的攻击。
Lancet. 2023 Feb 25;401(10377):617. doi: 10.1016/S0140-6736(23)00387-2.
4
Impact of Ukrainian- Russian War on Health Care and Humanitarian Crisis.乌克兰-俄罗斯战争对医疗保健和人道主义危机的影响。
Disaster Med Public Health Prep. 2022 Dec 7;17:e340. doi: 10.1017/dmp.2022.265.
5
Exposure to armed conflict as a factor associated with very low birth weight: Case-control population study.暴露于武装冲突作为与极低出生体重相关的因素:病例对照人群研究。
Int J Gynaecol Obstet. 2022 Sep;158(3):619-625. doi: 10.1002/ijgo.14082. Epub 2022 Jan 24.
6
Armed conflict and birth weight.武装冲突与出生体重。
Econ Hum Biol. 2020 Dec;39:100921. doi: 10.1016/j.ehb.2020.100921. Epub 2020 Aug 10.
7
Post-traumatic stress disorder and association with low birth weight in displaced population following conflict in Malakand division, Pakistan: a case control study.创伤后应激障碍与巴基斯坦马拉坎德分部冲突后流离失所人群低出生体重的关联:一项病例对照研究。
BMC Pregnancy Childbirth. 2020 Mar 17;20(1):166. doi: 10.1186/s12884-020-2841-2.
8
Adverse effects of exposure to armed conflict on pregnancy: a systematic review.武装冲突对妊娠的不良影响:一项系统评价
BMJ Glob Health. 2017 Nov 28;2(4):e000377. doi: 10.1136/bmjgh-2017-000377. eCollection 2017.
9
Stress and Birth Weight: Evidence from Terrorist Attacks.压力与出生体重:来自恐怖袭击的证据
Am Econ Rev. 2008 May;98(2):511-5.
10
Inequalities in uptake of prenatal screening according to ethnicity and socio-economic status in the four largest cities of the Netherlands (2011-2013).荷兰四大城市(2011-2013 年)按族裔和社会经济地位划分的产前筛查参与度不平等。
Prenat Diagn. 2017 Oct;37(10):959-967. doi: 10.1002/pd.5089. Epub 2017 Aug 14.

俄罗斯入侵后乌克兰出生体重下降的证据。

Evidence of reduced birthweight in Ukraine following the Russian invasion.

作者信息

Arbuzova Svitlana, Nikolenko Margaryta, Atramentova Liubov, Cuckle Howard

机构信息

Eastern-Ukrainian Center for Medical Genetics and Prenatal Diagnosis, Mariupol & Kyiv, Ukraine.

Institute of Health Research, University of Exeter, 16 Trinity Apartments, 3 Roman Wall, Exeter, Devon, EX1 1GP, England, UK.

出版信息

Sci Rep. 2025 Apr 25;15(1):14413. doi: 10.1038/s41598-025-98668-8.

DOI:10.1038/s41598-025-98668-8
PMID:40281104
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12032134/
Abstract

The impact of armed conflict on birth weight has been shown in various studies, but the effects of the full-scale Russian invasion of Ukraine in 2022 have been overlooked until now. This study investigates the influence of war on birth-weight using data and follow-up of pregnancies among women having prenatal screening. Maternal factors, outcomes, and birth weights were analyzed for 706 screened women who delivered between 2020 and 2023, excluding cases of spontaneous abortion, termination, and multiple pregnancies. Of these, 330 deliveries occurred before the invasion and 376 afterward. The only statistically significant maternal factors were parity - 22% nulliparous before and 48% after invasion (P < 0.0001) and maternal weight - 60 versus 62 kg. (P < 0.05). Birth-weight was significantly reduced: median 3500 g before and 3350 g after (P < 0.0001); proportions < 2500 g, 1.2% and 2.4%, respectively (P = 0.24). The ratio of birth-weight to infant length was also significant (P < 0.0001). Analysis of variance showed birth-weight significances remained after allowing for parity and gender. These findings highlight a significant decline in birth weight associated with armed conflict, emphasizing the need for targeted interventions to support maternal and neonatal health during periods of war.

摘要

武装冲突对出生体重的影响已在多项研究中得到证实,但2022年俄罗斯对乌克兰的全面入侵所产生的影响至今仍被忽视。本研究利用产前筛查女性的怀孕数据和随访情况,调查战争对出生体重的影响。对2020年至2023年期间分娩的706名接受筛查的女性的母亲因素、分娩结果和出生体重进行了分析,不包括自然流产、人工流产和多胎妊娠的情况。其中,330例分娩发生在入侵之前,376例发生在入侵之后。唯一具有统计学意义的母亲因素是产次——入侵前22%为初产妇,入侵后为48%(P<0.0001)以及母亲体重——分别为60公斤和62公斤(P<0.05)。出生体重显著降低:入侵前中位数为3500克,入侵后为3350克(P<0.0001);体重<2500克的比例分别为1.2%和2.4%(P=0.24)。出生体重与婴儿身长的比例也具有显著性(P<0.0001)。方差分析表明,在考虑产次和性别的因素后,出生体重的显著性仍然存在。这些发现凸显了与武装冲突相关的出生体重显著下降,强调了在战争期间需要采取有针对性的干预措施来保障孕产妇和新生儿的健康。