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俄罗斯入侵后乌克兰出生体重下降的证据。

Evidence of reduced birthweight in Ukraine following the Russian invasion.

作者信息

Arbuzova Svitlana, Nikolenko Margaryta, Atramentova Liubov, Cuckle Howard

机构信息

Eastern-Ukrainian Center for Medical Genetics and Prenatal Diagnosis, Mariupol & Kyiv, Ukraine.

Institute of Health Research, University of Exeter, 16 Trinity Apartments, 3 Roman Wall, Exeter, Devon, EX1 1GP, England, UK.

出版信息

Sci Rep. 2025 Apr 25;15(1):14413. doi: 10.1038/s41598-025-98668-8.

Abstract

The impact of armed conflict on birth weight has been shown in various studies, but the effects of the full-scale Russian invasion of Ukraine in 2022 have been overlooked until now. This study investigates the influence of war on birth-weight using data and follow-up of pregnancies among women having prenatal screening. Maternal factors, outcomes, and birth weights were analyzed for 706 screened women who delivered between 2020 and 2023, excluding cases of spontaneous abortion, termination, and multiple pregnancies. Of these, 330 deliveries occurred before the invasion and 376 afterward. The only statistically significant maternal factors were parity - 22% nulliparous before and 48% after invasion (P < 0.0001) and maternal weight - 60 versus 62 kg. (P < 0.05). Birth-weight was significantly reduced: median 3500 g before and 3350 g after (P < 0.0001); proportions < 2500 g, 1.2% and 2.4%, respectively (P = 0.24). The ratio of birth-weight to infant length was also significant (P < 0.0001). Analysis of variance showed birth-weight significances remained after allowing for parity and gender. These findings highlight a significant decline in birth weight associated with armed conflict, emphasizing the need for targeted interventions to support maternal and neonatal health during periods of war.

摘要

武装冲突对出生体重的影响已在多项研究中得到证实,但2022年俄罗斯对乌克兰的全面入侵所产生的影响至今仍被忽视。本研究利用产前筛查女性的怀孕数据和随访情况,调查战争对出生体重的影响。对2020年至2023年期间分娩的706名接受筛查的女性的母亲因素、分娩结果和出生体重进行了分析,不包括自然流产、人工流产和多胎妊娠的情况。其中,330例分娩发生在入侵之前,376例发生在入侵之后。唯一具有统计学意义的母亲因素是产次——入侵前22%为初产妇,入侵后为48%(P<0.0001)以及母亲体重——分别为60公斤和62公斤(P<0.05)。出生体重显著降低:入侵前中位数为3500克,入侵后为3350克(P<0.0001);体重<2500克的比例分别为1.2%和2.4%(P=0.24)。出生体重与婴儿身长的比例也具有显著性(P<0.0001)。方差分析表明,在考虑产次和性别的因素后,出生体重的显著性仍然存在。这些发现凸显了与武装冲突相关的出生体重显著下降,强调了在战争期间需要采取有针对性的干预措施来保障孕产妇和新生儿的健康。

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本文引用的文献

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