Wilcox M, Gardosi J, Mongelli M, Ray C, Johnson I
Department of Obstetrics and Gynaecology, Nottingham University, Queen's Medical Centre.
BMJ. 1993 Sep 4;307(6904):588-91. doi: 10.1136/bmj.307.6904.588.
To produce standard curves of birth weight according to gestational age validated by ultrasonography in the British population, with particular reference to the effects of ethnic origin.
Retrospective analysis of computerised obstetric database.
Three large maternity units associated with Nottingham University with over 16,000 deliveries a year.
41,718 women with ultrasound dated singleton pregnancies and delivery between 168 and 300 days' gestation.
Length of gestation, ethnic origin, parity, maternal height and weight at booking, smoking during pregnancy; the effect of these variables on birth weight.
Birth weights from ultrasound dated pregnancies have a higher population mean and show less flattening of the birthweight curve at term than those of pregnancies dated from menstrual history. Significant differences were observed in mean birth weights of babies of mothers of European origin (3357 g), of Afro-Caribbean origin (3173 g), and from the Indian subcontinent (3096 g). There were also significant interethnic differences in length of gestation, parity, maternal height, booking weight, and smoking habit which affected birth weight. The ethnic differences in birth weight were even greater when the effect of smoking was excluded.
Birthweight standards require precise dating of pregnancy and should describe the population from which they were derived. In a heterogeneous maternity population the accurate assessment of an individual baby's weight needs to take the factors which affect birthweight standards into consideration.
绘制英国人群中经超声检查验证的按孕周划分的出生体重标准曲线,特别关注种族起源的影响。
对计算机化产科数据库进行回顾性分析。
与诺丁汉大学相关的三个大型产科单位,每年分娩超过16000例。
41718名单胎妊娠且孕周在168至300天之间并经超声确定孕周的孕妇。
孕周、种族起源、产次、孕早期孕妇身高和体重、孕期吸烟情况;这些变量对出生体重的影响。
经超声确定孕周的妊娠出生体重的总体均值较高,且足月时出生体重曲线的平坦程度低于根据月经史确定孕周的妊娠。观察到欧洲裔母亲的婴儿平均出生体重(3357克)、非洲加勒比裔母亲的婴儿平均出生体重(3173克)和印度次大陆母亲的婴儿平均出生体重(3096克)存在显著差异。在孕周、产次、孕妇身高、孕早期体重和吸烟习惯方面也存在显著的种族间差异,这些因素会影响出生体重。排除吸烟影响后,出生体重的种族差异更大。
出生体重标准需要精确确定孕周,并应描述其来源人群。在异质的产科人群中,准确评估单个婴儿的体重需要考虑影响出生体重标准的因素。