Wojtczak Beata, Sępek Monika, Sutkowski Krzysztof, Marciniak Dominik, Kaliszewski Krzysztof
University Centre of General and Oncological Surgery, Wroclaw Medical University, Borowska Street 213, 50-556, Wroclaw, Poland.
Department of Dosage Form Technology, Wroclaw Medical University, Borowska Street 211 A, 50-556, Wroclaw, Poland.
Sci Rep. 2025 Apr 25;15(1):14432. doi: 10.1038/s41598-025-99191-6.
In the last 25 years, there have been significant advances in the diagnosis and treatment of thyroid disorders. The aim of this study was to analyze 25 years of experience in thyroid surgery in high volume endocrine center in terms of demographic changes, indications for surgical treatment, the type of thyroid surgery and complications. Clinical material (3748 patients) from the years 1996-2020 was analyzed by compering two Periods: I (1996-2003) vs. II (2011-2015/2018-2020). The percentage of patients operated on for thyroid cancer increased (p < 0.00001) and the extent of thyroid surgery changing from partial to total excision was statistically significant (p < 0.00001). The increase in the extent of thyroidectomy did not affect the overall recurrent laryngeal nerve palsy (p = 0.1785), but resulted in an increase of postoperative clinical hypoparathyroidism (p < 0.00001). The introduction of new technologies, such as intraoperative nerve monitoring of the recurrent laryngeal nerves had a significant impact on the changes in thyroid surgery over 25 years.
在过去25年中，甲状腺疾病的诊断和治疗取得了重大进展。本研究的目的是从人口统计学变化、手术治疗指征、甲状腺手术类型和并发症方面分析一家大型内分泌中心25年的甲状腺手术经验。通过比较两个时期：I期（1996 - 2003年）和II期（2011 - 2015年/2018 - 2020年），对1996年至2020年的临床资料（3748例患者）进行了分析。因甲状腺癌接受手术的患者百分比增加（p < 0.00001），甲状腺手术范围从部分切除转变为全切除具有统计学意义（p < 0.00001）。甲状腺切除范围的增加并未影响总体喉返神经麻痹（p = 0.1785），但导致术后临床甲状旁腺功能减退增加（p < 0.）。新技术的引入，如术中喉返神经监测，对25年来甲状腺手术的变化产生了重大影响。 00001
