谷子中BREVIS RADIX基因家族的全基因组鉴定：功能、进化与表达
Genome-Wide Identification of the BREVIS RADIX Gene Family in Foxtail Millet: Function, Evolution, and Expression.
作者信息
Yuan Xiaorui, Bai Xionghui, Yu Jin, Jia Zhijie, Wang Chenyu
机构信息
Maize Research Institute, Shanxi Agricultural University, Xinzhou 034000, China.
Development Center of Science and Technology, Ministry of Agriculture and Rural Affairs (MARA), Beijing 100176, China.
出版信息
Genes (Basel). 2025 Mar 25;16(4):374. doi: 10.3390/genes16040374.
BACKGROUND
Foxtail millet (), domesticated from green foxtail ), is crucial for global food security. Given increasing environmental challenges, exploring its stress-resistance mechanisms via researching the BREVIS RADIX (BRX) gene family is urgent.
METHODS
The study combines advanced bioinformatics and experimental validation. It uses phylogenetic, motif, domain, synteny analyses, miRNA prediction, and quantitative expression profiling under stress.
RESULTS
Phylogenetic analysis reveals new sub-clades and trajectories. Motif and domain analyses find new conserved elements. Statistical models show unique selective forces. Synteny analysis identifies genomic architecture and new blocks. miRNA prediction reveals gene-miRNA interactions, and expression profiling shows new patterns.
CONCLUSIONS
The research offers new insights into the BRX family's role in foxtail millet's growth and stress responses, laying a foundation for crop genetic improvement and enhancing stress resilience for global food security.
背景
谷子（Setaria italica）由青狗尾草（Setaria viridis）驯化而来，对全球粮食安全至关重要。鉴于环境挑战日益增加，通过研究短根（BREVIS RADIX，BRX）基因家族来探索其抗逆机制迫在眉睫。
方法
本研究结合了先进的生物信息学和实验验证。它运用了系统发育、基序、结构域、共线性分析、miRNA预测以及胁迫下的定量表达谱分析。
结果
系统发育分析揭示了新的亚分支和进化轨迹。基序和结构域分析发现了新的保守元件。统计模型显示了独特的选择力。共线性分析确定了基因组结构和新的基因块。miRNA预测揭示了基因与miRNA的相互作用，表达谱分析显示了新的模式。
结论
该研究为BRX家族在谷子生长和胁迫响应中的作用提供了新见解，为作物遗传改良奠定了基础，并增强了全球粮食安全的抗逆能力。
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