Stanciu Cristina-Teodora, Vermesan Dinu, Pop Daniel Laurentiu, Hogea Bogdan, Vlad Silviu Valentin
Doctoral School, "Victor Babes" University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.
Department XVI-Orthopedics, Traumatology, Urology, and Medical Imaging, Discipline of Orthopedics and Traumatology I, "Victor Babes" University of Medicine and Pharmacy Timisoara, 300041 Timisoara, Romania.
Life (Basel). 2025 Mar 21;15(4):511. doi: 10.3390/life15040511.
Optimizing functional recovery alongside wound healing remains a challenge in acute wound management. Negative Pressure Wound Therapy (NPWT) is widely used to promote tissue regeneration and reduce edema, yet its impact on functional outcomes and quality of life is less explored. This study evaluates the effects of NPWT alone versus NPWT combined with physiotherapy, focusing on functional recovery and patient-reported outcomes.
This prospective study included patients with acute wounds at the Timisoara County Emergency Clinical Hospital, treated between 2020 and 2024. Participants were divided into two groups: Group 1, receiving NPWT exclusively, and Group 2, undergoing NPWT combined with physiotherapy (Proprioceptive Neuro-muscular Facilitation, Kabat diagonals, manual lymphatic drainage, and proprioceptive exercises). Assessments included joint mobility (goniometry), edema (circumferential measurements), muscle strength (Manual Muscle Testing), and patient-reported outcomes using WHOQOL-BREF, SF-36, and HADS questionnaires.
Results demonstrated that, at 10 days, patients in the specialized physiotherapy group had significantly greater ankle dorsiflexion (18.10 ± 1.63°) compared to the classical group (10.05 ± 1.76°; < 0.001). Knee flexion in the specialized group was 134.58 ± 5.15° versus 115.57 ± 5.32° in the classical group ( < 0.001). Edema circumference and depth were reduced in both groups, with minor but notable improvements in the specialized group at later follow-ups ( < 0.05). Self-reported quality of life (SF-36, WHOQOL-BREF) and mental health (HADS) scores were slightly better at 10 days in the specialized group, although differences diminished by 6 months.
Combining NPWT with specialized physiotherapy techniques enhances functional recovery and quality of life in acute wound patients. These findings support the integration of multi-disciplinary rehabilitation to optimize patient outcomes.
在急性伤口处理中，优化功能恢复与伤口愈合仍是一项挑战。负压伤口治疗（NPWT）被广泛用于促进组织再生和减轻水肿，但其对功能结局和生活质量的影响鲜少被探究。本研究评估单纯NPWT与NPWT联合物理治疗的效果，重点关注功能恢复和患者报告的结局。
这项前瞻性研究纳入了2020年至2024年期间在蒂米什瓦拉县急诊临床医院接受治疗的急性伤口患者。参与者被分为两组：第1组仅接受NPWT，第2组接受NPWT联合物理治疗（本体感觉神经肌肉促进法、卡巴特对角线运动、手动淋巴引流和本体感觉训练）。评估包括关节活动度（测角法）、水肿（周径测量）、肌肉力量（徒手肌力测试），以及使用世界卫生组织生活质量简表（WHOQOL-BREF）、健康调查简表（SF-36）和医院焦虑抑郁量表（HADS）问卷进行的患者报告结局评估。
结果表明，在第10天时，专业物理治疗组患者的踝关节背屈角度（18.10±1.63°）显著大于传统组（10.05±1.76°；P<0.001）。专业组的膝关节屈曲角度为134.58±5.15°，而传统组为115.57±5.32°（P<0.001）。两组的水肿周径和深度均有所减小，在后期随访中，专业组有轻微但显著的改善（P<0.05）。在第10天时，专业组的自我报告生活质量（SF-36、WHOQOL-BREF）和心理健康（HADS）评分略高，不过到6个月时差异减小。
NPWT与专业物理治疗技术相结合可提高急性伤口患者的功能恢复和生活质量。这些发现支持多学科康复整合以优化患者结局。
