Nozais J P
Bull Soc Pathol Exot Filiales. 1985;78(2):256-63.
East Africa is separated from the continent by the Great Rift Valley which was created at the end of the secondary era limiting then the East Africa under-continent with peculiar fauna and flora features. A several million years long isolation, during the tertiary era, seems to explain that a certain number of protozoan and helminthic diseases present peculiar clinical, epidemiological, therapeutical and parasitological features. The occurrence of those peculiar strains tends to indicate that in this region, for example, the resistance of P. falciparum to amino-4-quinolines is a regional feature which should not largely expand to the rest of the African continent.
东非被大裂谷与非洲大陆分隔开来，大裂谷形成于中生代末期，当时东非次大陆具有独特的动植物特征。在第三纪时期长达数百万年的隔离似乎可以解释，一些原生动物和蠕虫疾病呈现出独特的临床、流行病学、治疗和寄生虫学特征。这些独特菌株的出现往往表明，例如在该地区，恶性疟原虫对4-氨基喹啉的耐药性是一种区域特征，不会在很大程度上扩展到非洲大陆的其他地区。
