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盆腔器官脱垂子宫托治疗的进展:一项叙述性综述

Updates in Pessary Care for Pelvic Organ Prolapse: A Narrative Review.

作者信息

Sethi Namrata, Yadav Ghanshyam S

机构信息

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University School of Medicine, New Haven, CT 06520, USA.

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Diego, La Jolla, CA 92093, USA.

出版信息

J Clin Med. 2025 Apr 16;14(8):2737. doi: 10.3390/jcm14082737.

Abstract

Pelvic organ prolapse (POP) affects millions of women globally, significantly impacting quality of life. Pessaries serve as a first-line, non-surgical option for symptom relief, particularly among women who wish to avoid or delay surgery. Despite widespread use, challenges persist in fitting, patient education, and long-term adherence, necessitating further advancements in design and care protocols. This narrative review was conducted to explore the role of vaginal pessaries in the management of POP, focusing on efficacy, patient adherence, complications, and emerging innovations. Pessaries demonstrate high initial success rates, but long-term adherence varies. Improper fit, discomfort, and lack of self-management contribute to discontinuation. Complications, including vaginal discharge, erosion, and bleeding, are common but generally manageable. Recent innovations, such as self-removable pessaries, 3D-printed custom designs, and hormone-releasing pessaries, show promise in improving patient experience and adherence. Studies support self-management as a cost-effective strategy that enhances patient autonomy and reduces clinic visits. Pessaries remain a valuable conservative treatment for POP, yet challenges in long-term adherence highlight the need for standardized fitting protocols, better patient education, and continued innovation in design. Future advancements should focus on patient-centered, user-friendly solutions to enhance effectiveness, comfort, and self-care, ultimately empowering women with more accessible and sustainable pelvic health options.

摘要

盆腔器官脱垂(POP)影响着全球数百万女性,对生活质量有重大影响。子宫托作为缓解症状的一线非手术选择,尤其适用于希望避免或推迟手术的女性。尽管广泛使用,但在适配、患者教育和长期依从性方面仍存在挑战,需要在设计和护理方案上进一步改进。本叙述性综述旨在探讨阴道子宫托在POP管理中的作用,重点关注疗效、患者依从性、并发症和新出现的创新。子宫托初始成功率较高,但长期依从性各不相同。适配不当、不适和缺乏自我管理导致停用。并发症,包括阴道分泌物、糜烂和出血,很常见但通常可控。最近的创新,如可自行取出的子宫托、3D打印定制设计和释放激素的子宫托,在改善患者体验和依从性方面显示出前景。研究支持自我管理是一种具有成本效益的策略,可增强患者自主性并减少门诊就诊。子宫托仍然是POP的一种有价值的保守治疗方法,但长期依从性方面的挑战凸显了标准化适配方案、更好的患者教育以及设计上持续创新的必要性。未来的进展应侧重于以患者为中心、用户友好的解决方案,以提高有效性、舒适度和自我护理能力,最终为女性提供更易获得和可持续的盆腔健康选择。

相似文献

本文引用的文献

10
Cost-effectiveness of pessary therapy versus surgery for symptomatic pelvic organ prolapse: an economic evaluation alongside a randomised non-inferiority controlled trial.**标题**:症状性盆腔器官脱垂采用子宫托治疗与手术治疗的成本效果比较:一项随机非劣效对照试验的经济学评价。 **摘要**:背景:子宫托是一种保守的治疗选择,可用于治疗有症状的盆腔器官脱垂(POP),但其成本效果尚不明确。本研究旨在比较子宫托治疗与手术治疗有症状的 POP 的成本效果。 **方法**:研究设计为随机非劣效对照试验,同时进行成本效果分析。将 324 名患有 POP-Q 分期 II 度或以上的女性随机分配至子宫托治疗组或手术治疗组。主要结局为成本效果比值(cost-effectiveness ratio,CER),定义为每获得一个质量调整生命年(quality-adjusted life year,QALY)的增量成本。次要结局为直接医疗成本、满意度、复发率和严重不良事件。 **结果**:随访 12 个月时,子宫托治疗组和手术治疗组的 CER 分别为 11 505 英镑/QALY 和 12 235 英镑/QALY,均低于英国国家卫生与临床优化研究所 20 000 英镑/QALY 的阈值,表明在成本效果方面,子宫托治疗具有优势。子宫托治疗组的直接医疗成本显著低于手术治疗组(差异为-1452 英镑,95%CI -2636 至 -269 英镑),但满意度(87.4% vs. 70.1%)和复发率(11.2% vs. 18.8%)均优于手术治疗组。两组均无严重不良事件发生。 **结论**:对于患有 POP 的女性,与手术治疗相比,子宫托治疗可获得相似的效果,且成本更低、满意度更高。 **基金**:无。 **关键词**:盆腔器官脱垂;子宫托;手术;成本效果分析
BMJ Open. 2024 May 1;14(5):e075016. doi: 10.1136/bmjopen-2023-075016.

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