Zawiasa Anna, Schmidt Marcin, Olejnik-Schmidt Agnieszka
Department of Food Biotechnology and Microbiology, Poznan University of Life Sciences, Wojska Polskiego 48, 60-627 Poznan, Poland.
Viruses. 2025 Mar 27;17(4):482. doi: 10.3390/v17040482.
, though considered non-pathogenic, frequently coexists with in industrial environments, aiding its survival in biofilms. These biofilms pose a significant challenge in food processing facilities, as they protect bacteria from disinfectants and facilitate their spread. The aim of this review was to identify bacteriophages as a promising method for eliminating biofilms from the food industry. Lytic bacteriophages show great potential in combating biofilms. Commercially available products, such as PhageGuard Listex™ (P100) (Micreos Food Safety, Wageningen, The Netherlands), effectively reduce both and in food products and on production surfaces. Additionally, phage-derived enzymes, such as endolysins, can degrade biofilms, eliminating bacteria without compromising food quality. The following article highlights that although bacteriophages present a promising biocontrol method, further research is necessary to assess their long-term effectiveness, particularly regarding bacterial resistance. To maximize efficacy, a combination of strategies such as phage cocktails and disinfectants is recommended to enhance biofilm eradication and minimize food contamination risks.
尽管被认为是非致病性的，但在工业环境中常与[未提及的细菌名称]共存，有助于其在生物膜中存活。这些生物膜在食品加工设施中构成了重大挑战，因为它们保护细菌免受消毒剂影响并促进其传播。本综述的目的是确定噬菌体是一种有前景的消除食品工业中[未提及的细菌名称]生物膜的方法。裂解性噬菌体在对抗[未提及的细菌名称]生物膜方面显示出巨大潜力。市售产品，如PhageGuard Listex™（P100）（荷兰瓦赫宁根的Micreos食品安全公司），能有效减少食品产品和生产表面的[未提及的细菌名称]和[未提及的细菌名称]。此外，噬菌体衍生的酶，如内溶素，可以降解生物膜，在不影响食品质量的情况下消除细菌。以下文章强调，尽管噬菌体是一种有前景的生物控制方法，但有必要进一步研究以评估其长期有效性，特别是关于细菌抗性方面。为了使功效最大化，建议结合使用噬菌体鸡尾酒和消毒剂等策略，以加强生物膜根除并将食品污染风险降至最低。
