Ravnskov U
Clin Nephrol. 1985 Jun;23(6):294-8.
Many hydrocarbons have properties which make them candidates for causing glomerulonephritis. They alter most immune functions and create a state of immunity deficiency; they damage the tubules which may lead to interstitial fibrosis and increased postglomerular capillary resistance furthering the trapping of macromolecules in the glomeruli; and they probably increase tissue permeability to macromolecules. The idea that hydrocarbons cause glomerulonephritis is supported by findings of an association between glomerulonephritis and hydrocarbon exposure, by findings of a relationship between tubulointerstitial damage and glomerular filtration rate in glomerulonephritis, and by findings of immunity deficiency in most subgroups of glomerulonephritis.
许多碳氢化合物具有一些特性，使其有可能引发肾小球肾炎。它们会改变大多数免疫功能并造成免疫缺陷状态；它们会损害肾小管，这可能导致间质纤维化，并增加肾小球后毛细血管阻力，进而促使大分子物质在肾小球中滞留；而且它们可能会增加组织对大分子物质的通透性。肾小球肾炎与碳氢化合物暴露之间存在关联的研究结果、肾小球肾炎中肾小管间质损伤与肾小球滤过率之间存在关系的研究结果，以及大多数肾小球肾炎亚组中存在免疫缺陷的研究结果，均支持碳氢化合物会引发肾小球肾炎这一观点。
