Tanaka Toshiyuki, Tsuruta Hana, Furukawa Koudai, Akiyoshi Hideo
Laboratory of Veterinary Advanced Diagnosis and Treatment, School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan.
Kinki Animal Medical Training Institute & Veterinary Clinic, Osaka, Japan.
Vet Med Sci. 2025 May;11(3):e70353. doi: 10.1002/vms3.70353.
In cats, eosinophilic enteritis (EE) is diagnosed when eosinophils are the predominant inflammatory cells on histopathology and no underlying trigger for their presence can be identified. Gastrointestinal eosinophilic sclerosing fibroplasia is a unique fibroblastic response of EE. Contrast-enhanced computed tomography (CT) facilitates the objective characterisation of intestinal lesions and associated pathology. To the best of our knowledge, there are no reports of CT findings in cats with EE. This case series retrospectively evaluated the CT findings of eight cats with EE including lesion location, intestinal wall layering structure, mass formation, location and size of lymph nodes, total wall thickness and outer intestinal layer relative thickness. The development of a layered intestinal wall appearance in the early and delayed phases was detected in seven (87.5%) and five cases (62.5%), respectively. All patients exhibited intestinal wall thickening, seven (87.5%) with marked thickening of the outer intestinal wall. Lesions were diffuse in all cats, involving the duodenum, jejunum and ileum in seven cats (87.5%) and in the ileum and colon in one cat (12.5%). Mass formation and lymphadenomegaly was detected in one (12.5%) and four cats (50%), respectively. The CT features of EE included thickening of the outer intestinal layer with development of a layered wall appearance and associated lymphadenomegaly.
在猫中,当嗜酸性粒细胞是组织病理学上的主要炎症细胞且无法确定其存在的潜在触发因素时,即可诊断为嗜酸性肠炎(EE)。胃肠道嗜酸性硬化性纤维增生是EE的一种独特的成纤维细胞反应。对比增强计算机断层扫描(CT)有助于对肠道病变及相关病理进行客观特征描述。据我们所知,尚无关于EE猫的CT表现的报道。本病例系列回顾性评估了8只EE猫的CT表现,包括病变位置、肠壁分层结构、肿块形成、淋巴结位置和大小、肠壁总厚度及外层肠壁相对厚度。在7例(87.5%)和5例(62.5%)中分别检测到早期和延迟期肠壁分层外观的形成。所有患者均表现出肠壁增厚,7例(87.5%)外层肠壁明显增厚。所有猫的病变均为弥漫性,7只猫(87.5%)累及十二指肠、空肠和回肠,1只猫(12.5%)累及回肠和结肠。分别在1只(12.5%)和4只猫(50%)中检测到肿块形成和淋巴结肿大。EE的CT特征包括外层肠壁增厚、肠壁分层外观形成及相关淋巴结肿大。