Chau Isabelle J, Cunningham Eric, Bornstein Rivka, Albinus Regina, Stidham Katrina R
School of Medicine, New York Medical College, Valhalla, New York, USA.
Department of Otolaryngology-Head & Neck Surgery, Westchester Medical Center, Valhalla, New York, USA.
Laryngoscope. 2025 Sep;135(9):3348-3355. doi: 10.1002/lary.32226. Epub 2025 Apr 26.
To assess the rate of obtaining intraoperative eSRT measurements in primary cochlear implant (CI) recipients while limiting the use of volatile anesthetics, such as sevoflurane.
In this prospective cohort study, thirty-one patients who underwent CI surgery with a Cochlear Americas device from January 2023 through March 2024 were included. Intraoperative eSRT testing at electrodes E1, E6, E12, E17, and E22 was performed on all patients. Sevoflurane was discontinued and confirmed undetectable at least 10 min prior to eSRT testing to avoid diminishing the stapedial reflex. The primary outcome measure was eSRT response rate at any electrode or pulse width.
Thirty-four CIs were placed in 31 patients, including three bilateral recipients. Eighty-five percent (29/34) of implants had at least one response at any electrode or pulse width; 71% (24/34) at pulse width 25 μs; and 82% (28/34) at 25 or 37 μs. Response rates were significantly higher at apical (E17, E22) and middle (E12) electrodes compared to basal electrodes (E1, E6) (p = 0.004). Comparisons also revealed significantly different eSRT values between apical, middle, and basal electrodes (p < 0.0001). Specifically, the basal electrode region had a greater median threshold (30.5 nC/phase) than apical (18.3 nC/phase; p < 0.0001) and middle (17.7 nC/phase; p < 0.001) regions.
Intraoperative eSRT is a feasible and effective way of obtaining an objective measurement that can potentially guide CI programming. Subsequent studies will investigate the relationship between intraoperative and postoperative eSRT in this patient cohort and determine how intraoperative eSRT may facilitate CI programming.
评估在原发性人工耳蜗(CI)植入受者中获取术中电刺激听性脑干反应(eSRT)测量值的比率,同时限制使用挥发性麻醉剂,如七氟烷。
在这项前瞻性队列研究中,纳入了2023年1月至2024年3月期间使用美国科利耳公司设备接受CI手术的31例患者。对所有患者在电极E1、E6、E12、E17和E22处进行术中eSRT测试。在eSRT测试前至少10分钟停用七氟烷并确认其检测不到,以避免减弱镫骨肌反射。主要结局指标是任一电极或脉冲宽度下的eSRT反应率。
31例患者共植入34个CI,其中包括3例双侧植入者。85%(29/34)的植入物在任一电极或脉冲宽度下至少有一次反应;在脉冲宽度25 μs时为71%(24/34);在25或37 μs时为82%(28/34)。与基底电极(E1、E6)相比,顶端(E17、E22)和中部(E12)电极的反应率显著更高(p = 0.004)。比较还显示顶端、中部和基底电极之间的eSRT值存在显著差异(p < 0.0001)。具体而言,基底电极区域的中位阈值(30.5 nC/相位)高于顶端(18.3 nC/相位;p < 0.0001)和中部(17.7 nC/相位;p < 0.001)区域。
术中eSRT是获得客观测量值的一种可行且有效的方法,该测量值可能指导CI编程。后续研究将调查该患者队列中术中与术后eSRT之间的关系,并确定术中eSRT如何促进CI编程。