基于骨折联络服务数据集的初次骨折后骨折复发的直接风险因素，以及与文献中报道的跌倒风险因素的比较。
Immediate risk factors for fracture recurrence after initial fractures, based on fracture liaison service dataset, and comparison with fall risk factors reported in the literature.
作者信息
Doussiere Marie, Hamidou Yannis, Moukarzel Vanessa, Bruy Pierre-Antoine, Deprez Valentine, Sobhy-Danial Jean-Marc, Fauvet Corinne, Fardellone Patrice, Goëb Vincent
机构信息
Department of Rheumatology, University Hospital of Amiens, Amiens, France.
出版信息
Eur Geriatr Med. 2025 Apr 26. doi: 10.1007/s41999-025-01219-7.
INTRODUCTION
The risk of subsequent fracture is highest within 2 years of the initial fracture. This study aimed to identify risk factors for subsequent fractures in individuals aged 50 and older and compare them with those for falls, which often overlap.
METHODS
We compared 150 patients with at least two fractures (2009-2019) to 150 controls with one fracture during the same period, adjusting for age, gender, and fracture site.
RESULTS
Univariate analysis linked subsequent fractures to history of fractures (pre-2009), excessive alcohol consumption, visual or hearing impairments, cognitive disorders, rural or nursing home residency, depressive syndrome, benzodiazepine, and hypnotic use. Multivariate analysis confirmed risks for decreased visual acuity and hypnotic use.
CONCLUSION
Subsequent fracture risk is associated with falls, but not all fall risk factors increase fracture recurrence. Identifying those at risk is critical for targeted osteoporosis management within fall prevention strategies.
引言
初次骨折后的2年内再次骨折的风险最高。本研究旨在确定50岁及以上人群再次骨折的风险因素，并将其与经常重叠的跌倒风险因素进行比较。
方法
我们将150例至少发生过两次骨折的患者（2009年至2019年）与150例同期仅发生过一次骨折的对照者进行比较，并对年龄、性别和骨折部位进行了调整。
结果
单因素分析将再次骨折与骨折病史（2009年前）、过量饮酒、视力或听力障碍、认知障碍、农村居住或养老院居住、抑郁综合征、苯二氮䓬类药物和催眠药物的使用联系起来。多因素分析证实了视力下降和使用催眠药物的风险。
结论
再次骨折风险与跌倒有关，但并非所有跌倒风险因素都会增加骨折复发率。识别有风险的人群对于在预防跌倒策略中进行有针对性的骨质疏松症管理至关重要。
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