Suppr超能文献

生活在中等收入国家的老年人发生严重骨折跌倒的危险因素:一项病例对照研究。

Risk factors for falls with severe fracture in elderly people living in a middle-income country: a case control study.

作者信息

Coutinho Evandro S F, Fletcher Astrid, Bloch Katia V, Rodrigues Laura C

机构信息

Department of Epidemiology, National School of Public Health, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.

出版信息

BMC Geriatr. 2008 Aug 26;8:21. doi: 10.1186/1471-2318-8-21.

Abstract

BACKGROUND

Fracture after falling has been identified as an important problem in public health. Most studies of risk factors for fractures due to falls have been carried out in developed countries, although the size of the elderly population is increasing fast in middle income countries. The objective of this paper is to identify risk factors for fall related to severe fractures in those aged 60 or more in a middle-income country.

METHODS

A case-control study was carried out in Rio de Janeiro-Brazil based general hospitals between 2002-2003. Two hundred-fifty hospitalised cases of fracture were matched with 250 community controls by sex, age group and living area. Data were collected for socio-demographic variables, health status and drugs used before the fall. A conditional logistic regression model was fitted to identify variables associated with the risk of fall related severe fracture.

RESULTS

Low body mass index, cognitive impairment, stroke and lack of urine control were associated with increased risk of severe fall related fractures. Benzodiazepines and muscle relaxants were also related to an increased risk of severe fractures while moderate use of alcohol was associated with reduced risk.

CONCLUSION

Although the association between benzodiazepines and fractures due to fall has been consistently demonstrated for old people, this has not been the case for muscle relaxant drugs. The decision to prescribe muscle relaxants for elderly people should take into account the risk of severe fracture associated with these drugs.

摘要

背景

跌倒后骨折已被确认为一个重要的公共卫生问题。尽管中等收入国家老年人口规模增长迅速,但大多数关于跌倒所致骨折风险因素的研究是在发达国家开展的。本文的目的是确定一个中等收入国家60岁及以上人群中与严重骨折相关的跌倒风险因素。

方法

2002年至2003年期间,在巴西里约热内卢的综合医院开展了一项病例对照研究。250例住院骨折病例按性别、年龄组和居住地区与250名社区对照进行匹配。收集了社会人口统计学变量、健康状况以及跌倒前使用药物的数据。采用条件逻辑回归模型来确定与跌倒相关严重骨折风险相关的变量。

结果

低体重指数、认知障碍、中风和尿失禁与跌倒相关严重骨折风险增加有关。苯二氮䓬类药物和肌肉松弛剂也与严重骨折风险增加有关,而适度饮酒则与风险降低有关。

结论

尽管苯二氮䓬类药物与老年人跌倒所致骨折之间的关联已得到一致证实,但肌肉松弛剂药物并非如此。为老年人开具肌肉松弛剂时应考虑到这些药物与严重骨折相关的风险。

相似文献

2
[Medication as a risk factor for falls resulting in severe fractures in the elderly].
Cad Saude Publica. 2002 Sep-Oct;18(5):1359-66. doi: 10.1590/s0102-311x2002000500029.
3
Characteristics and circumstances of falls leading to severe fractures in elderly people in Rio de Janeiro, Brazil.
Cad Saude Publica. 2009 Feb;25(2):455-9. doi: 10.1590/s0102-311x2009000200024.
4
[Dementia as risk factor for severe bone fractures among the elderly].
Rev Saude Publica. 2002 Aug;36(4):448-54. doi: 10.1590/s0034-89102002000400010.
7
Incidence and characteristics of falls leading to hip fracture in Iranian population.
Bone. 2006 Aug;39(2):408-13. doi: 10.1016/j.bone.2006.01.144. Epub 2006 Feb 28.
8
Multifactorial and multiple component interventions for preventing falls in older people living in the community.
Cochrane Database Syst Rev. 2018 Jul 23;7(7):CD012221. doi: 10.1002/14651858.CD012221.pub2.
9
Risk factors for falls as a cause of hip fracture in women. The Northeast Hip Fracture Study Group.
N Engl J Med. 1991 May 9;324(19):1326-31. doi: 10.1056/NEJM199105093241905.

引用本文的文献

1
Hip Fractures: Clinical, Biomaterial and Biomechanical Insights into a Common Health Challenge.
Bioengineering (Basel). 2025 May 28;12(6):580. doi: 10.3390/bioengineering12060580.
4
Outcomes of hip fracture in centenarians: a systematic review and meta-analysis.
Eur Geriatr Med. 2023 Dec;14(6):1223-1239. doi: 10.1007/s41999-023-00866-y. Epub 2023 Oct 4.
5
A Scoping Review to Assess Risk of Fracture Associated with Anxiolytic Medications.
Kans J Med. 2023 Aug 24;16(2):222-227. doi: 10.17161/kjm.vol16.20091. eCollection 2023.
6
Cardiovascular Disorders and Falls Among Older Adults: A Systematic Review and Meta-Analysis.
J Gerontol A Biol Sci Med Sci. 2024 Feb 1;79(2). doi: 10.1093/gerona/glad221.
8
The importance of alcohol in elderly's hospital admissions for fall injuries: a population case-control study.
Nordisk Alkohol Nark. 2022 Feb;39(1):38-49. doi: 10.1177/14550725211015836. Epub 2021 May 17.
10
Risk of Fall among Older Adults and its Association with Cognitive Impairment in a Semi-Urban Community.
Indian J Community Med. 2020 Oct-Dec;45(4):463-466. doi: 10.4103/ijcm.IJCM_491_19. Epub 2020 Oct 28.

本文引用的文献

1
Medication as a risk factor for falls: critical systematic review.
J Gerontol A Biol Sci Med Sci. 2007 Oct;62(10):1172-81. doi: 10.1093/gerona/62.10.1172.
2
National outpatient medication profiling: medications associated with outpatient fractures in community-dwelling elderly veterans.
Br J Clin Pharmacol. 2007 Feb;63(2):238-44. doi: 10.1111/j.1365-2125.2006.02798.x. Epub 2006 Nov 10.
3
Health-protective behaviours and risk of fall-related hip fractures: a population-based case-control study.
Age Ageing. 2006 Sep;35(5):491-7. doi: 10.1093/ageing/afl056. Epub 2006 Jun 13.
6
9
Risk indicators for falls in institutionalized frail elderly.
Am J Epidemiol. 2003 Oct 1;158(7):645-53. doi: 10.1093/aje/kwg203.
10
The costs of benzodiazepine-associated hospital-treated fall Injuries in the EU: a Pharmo study.
Drugs Aging. 2003;20(11):833-9. doi: 10.2165/00002512-200320110-00004.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验