Zerth Simon Felix, Basedow Lukas Andreas, Rief Winfried, Bingel Ulrike, Euteneuer Frank, Riecke Jenny, Wilhelm Marcel, Salzmann Stefan
Clinical Psychology and Psychotherapy, Department of Psychology, Philipps University of Marburg, Gutenbergstraße 18, 35032, Marburg, Germany.
Center for Translational Neuro- and Behavioral Sciences, Department of Neurology, University Medicine Essen, Hufelandstraße 55, 45147, Essen, Germany.
Sci Rep. 2025 Apr 26;15(1):14687. doi: 10.1038/s41598-025-98614-8.
Many individuals suffering from chronic pain do not benefit sufficiently from treatment. Prior treatment experiences and treatment expectations play a significant role in perceived symptom severity and treatment-related outcomes in many chronic diseases. Their role in chronic pain, however, remains underexplored. Therefore, the present study investigated the role of treatment experiences and treatment expectations for pain-related disability in individuals suffering from chronic pain. Participants suffering from chronic pain who were receiving treatment (pharmacotherapy, physiotherapy, and/or psychotherapy) completed questionnaires as part of an online survey. Prior improvement, worsening, and side effect experiences and their relation with treatment expectations were assessed with the generic rating scale for previous treatment experiences, treatment expectations, and treatment effects (GEEE), and pain-related disability via the pain disability questionnaire (PDI). Multiple linear regressions were performed to determine how prior treatment experiences related to treatment expectations and whether prior experiences and current treatment expectations were associated with pain-related disability. In total, 212 participants (86.3% female) were included. Prior worsening experience as well as stronger worsening and side effect expectations were associated with higher pain-related disability. Screening patients for different expectation domains could be an important strategy to detect and target potentially relevant factors influencing pain-related disability and treatment outcome.
许多慢性疼痛患者未能从治疗中充分获益。既往治疗经历和治疗期望在许多慢性疾病的感知症状严重程度及治疗相关结果中起着重要作用。然而，它们在慢性疼痛中的作用仍未得到充分研究。因此，本研究调查了治疗经历和治疗期望在慢性疼痛患者疼痛相关残疾中的作用。正在接受治疗（药物治疗、物理治疗和/或心理治疗）的慢性疼痛患者作为在线调查的一部分完成了问卷。使用既往治疗经历、治疗期望和治疗效果通用评定量表（GEEE）评估既往改善、恶化和副作用经历及其与治疗期望的关系，并通过疼痛残疾问卷（PDI）评估疼痛相关残疾。进行多元线性回归以确定既往治疗经历与治疗期望的关系，以及既往经历和当前治疗期望是否与疼痛相关残疾相关。总共纳入了212名参与者（86.3%为女性）。既往恶化经历以及更强的恶化和副作用期望与更高的疼痛相关残疾相关。筛查患者的不同期望领域可能是检测和针对影响疼痛相关残疾和治疗结果的潜在相关因素的重要策略。
