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识别复发性轻度缺血性中风的危险因素及高危人群特征:一项为期1年的随访研究。

Identifying risk factors for recurrent mild ischemic stroke and high-risk population characteristics: A 1-year follow-up study.

作者信息

Huang Shangmeng, Wu Zhengyu, Lan Wenbin, Huang Junqing, Wan Huijuan, Wang Dewen, Chen Jin Han

机构信息

The First Affiliated Hospital, Xiamen University, Xiamen, China.

School of Public Affairs, Xiamen University, Xiamen, China.

出版信息

J Int Med Res. 2025 Apr;53(4):3000605251332585. doi: 10.1177/03000605251332585. Epub 2025 Apr 27.

Abstract

ObjectiveThis observational study examined the risk factors associated with recurrence in patients with mild ischemic stroke and determined the characteristics of high-risk groups.MethodsA total of 656 patients hospitalized for mild ischemic stroke were monitored for 1 year. Statistical analyses, including odds ratio calculations and K-means clustering, were conducted to examine risk factors for recurrence and the characteristics of high-risk groups.ResultsAfter 1 year of follow-up, 99 patients experienced recurrent mild ischemic stroke, resulting in a recurrence rate of 15.09%. The analysis revealed several significant risk factors, including type 2 diabetes mellitus, atrial fibrillation, smoking and alcohol consumption, carotid artery stenosis, cerebral vascular stenosis, and multiple lesions. Propensity score matching confirmed these associations, and K-means clustering revealed that older males with type 2 diabetes mellitus and hypertension were likely to be in the high-risk group.ConclusionsHealthcare professionals should focus on tailored treatment and prevention strategies for high-risk patients, prioritizing the management of the abovementioned risk factors to reduce recurrence and improve outcomes.

摘要

目的

本观察性研究探讨了轻度缺血性脑卒中患者复发的相关危险因素,并确定了高危人群的特征。

方法

对656例因轻度缺血性脑卒中住院的患者进行了为期1年的监测。进行了包括比值比计算和K均值聚类在内的统计分析,以研究复发的危险因素和高危人群的特征。

结果

随访1年后,99例患者发生复发性轻度缺血性脑卒中,复发率为15.09%。分析发现了几个重要的危险因素,包括2型糖尿病、心房颤动、吸烟和饮酒、颈动脉狭窄、脑血管狭窄和多发病变。倾向评分匹配证实了这些关联,K均值聚类显示,患有2型糖尿病和高血压的老年男性可能属于高危人群。

结论

医疗保健专业人员应关注针对高危患者的个性化治疗和预防策略,优先管理上述危险因素,以降低复发率并改善预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c2e/12035232/9575fee71652/10.1177_03000605251332585-fig1.jpg

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