AbuAlrob Hajar, Afeef Vehra Muhammad, Shurman Abdallah, Shulkin Alexandra, Azizudin Ashlee, Hillier Loretta, Ioannidis George, Thabane Lehana, Griffith Lauren E, Costa Andrew P, Papaioannou Alexandra
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada
Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
BMJ Open. 2025 Apr 27;15(4):e093893. doi: 10.1136/bmjopen-2024-093893.
This review summarises the impact of hip fractures on health outcomes including subsequent falls, hospitalisation, length of hospital stay (LOS), functional status, quality of life and mortality in older adults with cognitive impairment or dementia. It also explores the risk of institutionalisation following a hip fracture in this population.
A scoping review following the Arksey and O'Malley framework guided by the Joanna Briggs Institute methodology and adheres to Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for Scoping Reviews guidelines.
A comprehensive search strategy was developed to search MEDLINE, EMBASE, CINAHL and grey literature, with additional references identified through citation searching and Web of Science.
Studies were included if they examined older adults with cognitive impairment or dementia who experienced a hip fracture and reported outcomes related to hospitalisation, functional status, quality of life, mortality or institutionalisation.
Study selection and data extraction were conducted independently by two reviewers using Covidence software. A narrative synthesis approach was employed to summarise findings and identify key themes, patterns and gaps in the literature.
We identified 30 studies reporting health outcomes following hip fracture. Overall, the studies indicated that individuals with cognitive impairment or dementia have higher hospitalisation rates, poorer walking ability and functional outcomes, as well as reduced quality of life posthip fracture. The LOS for individuals with dementia following hip fracture was inconsistent across studies, with some reporting shorter LOS and others indicating longer LOS. Individuals with dementia consistently exhibit higher mortality rates at 30 days, 90 days and 1-year postfracture compared with those without dementia. We found 21 studies that evaluated the risk of institutionalisation following a hip fracture. Older adults with dementia were significantly more likely to be institutionalised posthip fracture, with nearly five times the risk of failing to return home compared with those without dementia. This increased risk persists up to 1-year postfracture and is particularly pronounced in those with severe cognitive impairment, with higher rates of nursing home placement observed among individuals with hip fractures.
Older adults with cognitive impairment or dementia experience significantly worse outcomes following hip fractures, including higher mortality, poorer functional outcomes, reduced quality of life and a higher risk of institutionalisation postfracture. Future research should focus on developing effective strategies for fracture prevention, including optimising osteoporosis treatment in this high-risk population, and developing targeted interventions to improve the impact of fractures on functional outcomes and reduce institutionalisation rates in this vulnerable population.
本综述总结了髋部骨折对健康结局的影响,包括认知障碍或痴呆的老年人随后的跌倒、住院、住院时间(LOS)、功能状态、生活质量和死亡率。它还探讨了该人群髋部骨折后入住机构的风险。
遵循阿克斯西和奥马利框架进行的范围综述,由乔安娜·布里格斯研究所方法指导,并遵循系统评价和Meta分析扩展的范围综述首选报告项目指南。
制定了全面的检索策略,以检索MEDLINE、EMBASE、CINAHL和灰色文献,并通过引文检索和科学网确定了其他参考文献。
如果研究调查了经历髋部骨折的认知障碍或痴呆的老年人,并报告了与住院、功能状态、生活质量、死亡率或入住机构相关的结局,则纳入研究。
由两名评审员使用Covidence软件独立进行研究选择和数据提取。采用叙述性综合方法总结研究结果,并确定文献中的关键主题、模式和差距。
我们确定了30项报告髋部骨折后健康结局的研究。总体而言,研究表明,认知障碍或痴呆的个体住院率更高,步行能力和功能结局更差,髋部骨折后生活质量也更低。髋部骨折后痴呆患者的住院时间在各研究中不一致,一些研究报告住院时间较短,另一些研究表明住院时间较长。与无痴呆的个体相比,痴呆个体在骨折后30天、90天和1年时的死亡率始终较高。我们发现21项研究评估了髋部骨折后入住机构的风险。痴呆的老年人髋部骨折后入住机构的可能性显著更高,与无痴呆的个体相比,未能回家的风险几乎高出五倍。这种增加的风险在骨折后长达1年的时间内持续存在,在严重认知障碍的个体中尤为明显,髋部骨折患者中观察到更高的养老院安置率。
认知障碍或痴呆的老年人髋部骨折后的结局明显更差,包括更高的死亡率、更差的功能结局、更低的生活质量以及骨折后入住机构的风险更高。未来的研究应侧重于制定有效的骨折预防策略,包括在这一高危人群中优化骨质疏松症治疗,以及制定有针对性的干预措施,以改善骨折对功能结局的影响,并降低这一脆弱人群的入住机构率。