Zumtobel V, Finke U, Schäfer K
Chirurg. 1985 Jun;56(6):382-5.
From 1979 till 1984 a modified partial duodenopancreatectomy was performed in 22 patients with preservation of the stomach, proximal gastric vagotomy, and occlusion of the pancreatic duct. If occlusion of the duct was performed without a pancreatojejunostomy 6 of 12 patients developed a spontaneously healing pancreatic fistula. In 10 patients with duct occlusion and a pancreatojejunostomy no fistulae were observed. Exocrine and, if necessary, endocrine pancreatic insufficiency could be compensated sufficiently medically and by diet. In comparison to the original Whipple's operation preservation of the stomach seems to influence favourably the body weight and thus the quality of life. The proximal gastric vagotomy is performed to prevent anastomic ulcers.
1979年至1984年期间,对22例患者实施了改良的部分十二指肠胰腺切除术,保留胃、行近端胃迷走神经切断术并结扎胰管。若结扎胰管时未行胰空肠吻合术,12例患者中有6例发生了可自愈的胰瘘。在10例行胰管结扎及胰空肠吻合术的患者中,未观察到胰瘘。胰腺外分泌功能不全(必要时还有内分泌功能不全)可通过药物及饮食得到充分代偿。与最初的惠普尔手术相比,保留胃似乎对体重有积极影响,进而对生活质量产生积极影响。实施近端胃迷走神经切断术是为了预防吻合口溃疡。