Wang Yufan, Zhu Lina
Yufan Wang, Department of Anesthesiology, Zhejiang Rongjun Hospital, 309 Shuangyuan Road, Jiaxing, Zhejiang Province 314000, P.R. China.
Lina Zhu, Department of Anesthesiology, Zhejiang Rongjun Hospital, 309 Shuangyuan Road, Jiaxing, Zhejiang Province 314000, P.R. China.
Pak J Med Sci. 2025 Apr;41(4):1193-1201. doi: 10.12669/pjms.41.4.11531.
The current systematic review was conducted to compare quadratus lumborum block (QLB) vs fascia iliaca block (FIB) and femoral nerve block (FNB) for improving analgesic outcomes in patients undergoing hip surgeries.
We searched for randomized controlled trials from inception to on Embase, PubMed, Web of Science, clinical trial registry, and Google Scholar comparing QLB vs FIB/FNB for hip surgeries. The search was initiated on 1 December and culminated on 5 December 2023 to include all studies published from inception till the last day of the search. The primary outcome was 24 hours total analgesic consumption in morphine equivalents. Secondary outcomes were pain scores and incidence of quadriceps weakness at 24 hours, and postoperative nausea and vomiting (PONV).
Six RCTs were eligible. The meta-analysis found that 24-hours morphine consumption was found to be significantly lower in the FIB/FNB group as compared to the QLB group. Pain scores on the 10-point scale were not significantly different between the two groups at one to two hours, two to four hours, 12 hours, 24 hours, and 48 hours. Incidence of quadriceps weakness and PONV was also not significantly difference between the two groups.
Meta-analysis of a limited number of RCTs shows that QLB does not provide better postoperative analgesia as compared to FIB/FNB after hip surgery. Twenty four hours total opioid consumption was significantly higher with QLB but without any difference in pain scores. Incidence of quadriceps weakness and PONV does not differ between QLB and FIB/FNB.
进行本次系统评价以比较腰方肌阻滞(QLB)与髂筋膜阻滞(FIB)及股神经阻滞(FNB)在改善髋关节手术患者镇痛效果方面的差异。
我们在Embase、PubMed、Web of Science、临床试验注册库和谷歌学术上检索了从开始到2023年12月5日的随机对照试验,比较QLB与FIB/FNB用于髋关节手术的情况。检索于12月1日开始,至2023年12月5日结束,以纳入从开始到检索最后一天发表的所有研究。主要结局是24小时吗啡当量的总镇痛药物消耗量。次要结局包括24小时时的疼痛评分、股四头肌无力发生率以及术后恶心呕吐(PONV)。
六项随机对照试验符合纳入标准。荟萃分析发现,与QLB组相比,FIB/FNB组24小时吗啡消耗量显著更低。在1至2小时、2至4小时、12小时、24小时和48小时时,两组间10分制疼痛评分无显著差异。两组间股四头肌无力发生率和PONV发生率也无显著差异。
对有限数量随机对照试验的荟萃分析表明,髋关节手术后,与FIB/FNB相比,QLB并未提供更好的术后镇痛效果。QLB组24小时总阿片类药物消耗量显著更高,但疼痛评分无差异。QLB与FIB/FNB之间股四头肌无力发生率和PONV发生率无差异。