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2019 - 2020年智利圣地亚哥内乱期间催泪剂氯苯乙酮和辣椒油树脂的短期健康影响。

Short-term health effects of tear agents chlorobenzylidenemalononitrile and oleoresin capsicum during the civil riots of Santiago de Chile in 2019-2020.

作者信息

Jara Bravo Carlos, Cernuda Martínez José Antonio, Arcos González Pedro

机构信息

Unit for Research in Emergency and Disasters, Faculty of Medicine, University of Oviedo, Campus del Cristo, 33006 Oviedo, Spain.

出版信息

Toxicol Res. 2025 Feb 27;41(3):291-301. doi: 10.1007/s43188-025-00282-3. eCollection 2025 May.

Abstract

Chlorobenzylidenemalononitrile (CS) and Oleoresin Capsicum (OC) were tear gasses used as anti-riot control agents during social unrest riots in Chile (October 2019-March 2020). This study posed as a research question what were the short-term health effects of CS and OC and their patterns of temporal occurrence in a sample of inhabitants and health care volunteer brigades of the Plaza Italia (city of Santiago, Chile) during the riots. A retrospective cross-sectional study was conducted in 112 exposed people (inhabitants and health care volunteers) affected by CS and OC. 62 harmful effects were studied classified in three time periods of occurrence: immediate effects (between exposure and one hour), secondary effects (from one hour after exposure and up to 24 h), and subsequent effects (days after exposure). The use of CS and OC in Santiago riots 2019-2020 produced harmful effects on both groups: inhabitants and brigade health care volunteers. The frequency of effects was, from most to least common: 62.5% eye pain or burning, 56.2% throat irritation, 54.4% respiratory distress, 52.6% skin pain or burning, 51.7% impaired vision, 37.5% skin erythema, 31.2% headache, 31.2% irregular breathing, 25.8% conjunctival injection, 29.4% nausea, 27.6% disorientation, 26.7 high blood pressure, 25.8% lip pain, 24.1% rhinitis, 24.1% skin sensitivity, 22.3% diarrhea, 20.5% contact dermatitis, 18.7% conjunctivitis, 16.9% skin vesicles, 16% tachycardia, 14.4 cough with phlegm and 9.8% corneal abrasion. 22 effects were more frequent ( < 0.05) in health care volunteers than among residents. High blood pressure was more frequent ( < 0.05) among residents. Immediate most frequent effects were pain or burning, impaired vision, respiratory difficulty, irregular breathing, skin pain and burning, skin erythema, nausea, tachycardia, and hypertension. Secondary effects were diarrhea, skin vesicles, and eye pain or burning. Subsequent most frequent effects among healthcare personnel were conjunctivitis, skin pain, burning, rhinitis, and diarrhea. Among residents, the most common effects were skin pain, burning, and impaired vision.

摘要

氯苄叉丙二腈(CS)和辣椒油树脂(OC)是在智利社会动荡骚乱期间(2019年10月至2020年3月)用作防暴控制剂的催泪瓦斯。本研究提出了一个研究问题:在骚乱期间,智利圣地亚哥市意大利广场的居民和医疗志愿者样本中,CS和OC的短期健康影响及其时间发生模式是什么。对112名受CS和OC影响的暴露人群(居民和医疗志愿者)进行了一项回顾性横断面研究。研究了62种有害影响,分为三个发生时间段:即时影响(暴露后1小时内)、继发影响(暴露后1小时至24小时)和后续影响(暴露后数天)。2019 - 2020年圣地亚哥骚乱中CS和OC的使用对居民和医疗志愿者这两组人群都产生了有害影响。影响的频率从高到低依次为:62.5%眼痛或灼痛、56.2%咽喉刺激、54.4%呼吸窘迫、52.6%皮肤疼痛或灼痛、51.7%视力受损、37.5%皮肤红斑、31.2%头痛、31.2%呼吸不规则、25.8%结膜充血、29.4%恶心、27.6%定向障碍、26.7%高血压、25.8%唇部疼痛、24.1%鼻炎、24.1%皮肤敏感、22.3%腹泻、20.5%接触性皮炎、18.7%结膜炎、16.9%皮肤水疱、16%心动过速、14.4%咳痰咳嗽和9.8%角膜擦伤。22种影响在医疗志愿者中比在居民中更频繁(<0.05)。高血压在居民中更频繁(<0.05)。即时最常见的影响是疼痛或灼痛、视力受损、呼吸困难、呼吸不规则、皮肤疼痛和灼痛、皮肤红斑、恶心、心动过速和高血压。继发影响是腹泻、皮肤水疱和眼痛或灼痛。医疗人员后续最常见的影响是结膜炎、皮肤疼痛、灼痛、鼻炎和腹泻。在居民中,最常见的影响是皮肤疼痛、灼痛和视力受损。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5921/12022201/1861b506df90/43188_2025_282_Fig1_HTML.jpg

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