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双侧特发性巩膜脉络膜钙化:一例报告

Bilateral Idiopathic Sclerochoroidal Calcification: A Case Report.

作者信息

Azarkan Boutayna, Lazaar Hamza, Hilali Zineb, Boutimzine Noureddine, Cherkaoui Lalla Ouafa

机构信息

Ophtalmology A, Hopital des Specialités, CHU (Le Centre Hospitalo-Universitaire) Ibn Sina, Rabat, MAR.

Ophthalmology A, Hopital des Specialités, CHU (Le Centre Hospitalo-Universitaire) Ibn Sina, Rabat, MAR.

出版信息

Cureus. 2025 Mar 28;17(3):e81369. doi: 10.7759/cureus.81369. eCollection 2025 Mar.

DOI:10.7759/cureus.81369
PMID:40291202
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12034328/
Abstract

Sclerochoroidal calcification (SCC) is a rare and often asymptomatic condition characterized by the deposition of calcium pyrophosphate in the sclera and choroid. It predominantly affects elderly individuals of Caucasian descent and is most often idiopathic, although it can be secondary to systemic disorders such as hyperparathyroidism or chronic renal disease. The lesions appear as irregular, white-yellow plaques located in the mid-periphery, typically along the vascular arcades. We present the case of an 80-year-old patient with bilateral idiopathic SCC, incidentally discovered during an ophthalmologic examination. The patient's medical history included diabetes, hypertension, and cataract surgery, and there was no history of high myopia or uveitis. Fundus examination revealed yellowish choroidal lesions bilaterally, confirmed by autofluorescence and optical coherence tomography (OCT) imaging as elevated sclerochoroidal plaques. Comprehensive systemic and laboratory evaluations excluded underlying metabolic or renal abnormalities, confirming the idiopathic nature of the calcifications. The patient remained asymptomatic, and no treatment was required. This case underscores the importance of considering SCC in the differential diagnosis of elevated choroidal lesions. It highlights the need for thorough systemic evaluations to exclude secondary causes and emphasizes the generally benign prognosis of idiopathic cases.

摘要

巩膜脉络膜钙化(SCC)是一种罕见且通常无症状的病症,其特征是焦磷酸钙在巩膜和脉络膜中沉积。它主要影响白种人后裔的老年人,并且最常见为特发性的,尽管它可能继发于全身性疾病,如甲状旁腺功能亢进或慢性肾病。病变表现为位于中周边部的不规则白色 - 黄色斑块,通常沿着血管弓。我们报告一例80岁双侧特发性SCC患者,在眼科检查中偶然发现。患者的病史包括糖尿病、高血压和白内障手术,无高度近视或葡萄膜炎病史。眼底检查显示双侧脉络膜病变呈淡黄色,经自发荧光和光学相干断层扫描(OCT)成像证实为隆起的巩膜脉络膜斑块。全面的全身和实验室评估排除了潜在的代谢或肾脏异常,证实了钙化的特发性性质。患者无症状,无需治疗。该病例强调了在脉络膜病变隆起的鉴别诊断中考虑SCC的重要性。它突出了进行全面全身评估以排除继发原因的必要性,并强调了特发性病例通常良好的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56e/12034328/7e87f3b36090/cureus-0017-00000081369-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56e/12034328/c1161fe65af2/cureus-0017-00000081369-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56e/12034328/8c3bdda78917/cureus-0017-00000081369-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56e/12034328/5de2f6f222c1/cureus-0017-00000081369-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56e/12034328/7e87f3b36090/cureus-0017-00000081369-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56e/12034328/c1161fe65af2/cureus-0017-00000081369-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56e/12034328/8c3bdda78917/cureus-0017-00000081369-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56e/12034328/5de2f6f222c1/cureus-0017-00000081369-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b56e/12034328/7e87f3b36090/cureus-0017-00000081369-i04.jpg

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Clinical features and therapeutic management of choroidal osteoma: A systematic review.脉络膜骨瘤的临床特征与治疗管理:一项系统综述
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Multimodal Imaging of Choroidal Neovascularization Associated with Sclerochoroidal Calcification.与巩膜脉络膜钙化相关的脉络膜新生血管的多模态成像
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