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一例双侧广泛性特发性巩膜脉络膜钙化病例及文献综述

A Case of Extensive Bilateral Idiopathic Sclerochoroidal Calcification and Review of Literature.

作者信息

Thomson Andrew C, Brown Gordon T, Dolores-Rodriguez Angel, Hunter Allan A

机构信息

McGovern Medical School at The University of Texas Health Science Center at Houston, Houston, TX, USA.

Oregon Eye Consultants LLC, Eugene, OR, USA.

出版信息

Int Med Case Rep J. 2021 Oct 28;14:749-755. doi: 10.2147/IMCRJ.S336237. eCollection 2021.

Abstract

A 62-year-old Caucasian male was referred to retina for choroiditis and uveitis. Multiple areas of yellow irregularities were noted on fundus exam throughout the periphery of both eyes, corresponding to lesions at the sclerochoroidal junction on OCT. A diagnosis of sclerochoroidal calcifications (SCC) was confirmed by B-ultrasonography, fundus photography, OCT imaging, and fluorescein and indocyanine green angiography. Systemic metabolic studies were performed, which showed reduced renal function with increased serum calcium; however, SCC lesions in this case were most likely idiopathic. In this work, we report the clinical findings, appearance on multimodal imaging, and systemic associations of sclerochoroidal calcification. Sclerochoroidal calcifications are an unusual clinical finding that tends to be idiopathic, but a focused workup and specialist referral may be warranted to exclude systemic conditions associated with abnormal calcium-phosphate metabolism or hypokalemic metabolic alkalosis syndromes.

摘要

一名62岁的白种男性因脉络膜炎和葡萄膜炎被转诊至视网膜科。眼底检查发现双眼周边多个区域有黄色不规则病变,光学相干断层扫描(OCT)显示对应于巩膜脉络膜交界处的病变。B超、眼底照相、OCT成像以及荧光素和吲哚菁绿血管造影证实为巩膜脉络膜钙化(SCC)。进行了全身代谢研究,结果显示肾功能减退且血清钙升高;然而,该病例中的SCC病变很可能是特发性的。在本研究中,我们报告了巩膜脉络膜钙化的临床发现、多模态成像表现以及全身相关性。巩膜脉络膜钙化是一种不常见的临床发现,往往是特发性的,但可能需要进行针对性检查并转诊给专科医生,以排除与钙磷代谢异常或低钾性代谢性碱中毒综合征相关的全身性疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8816/8560165/dc7d3216acf3/IMCRJ-14-749-g0001.jpg

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