Syed Rohail, Boggula Ramesh, Jaenisch Harriett S, Joiner Michael C, Miller Steven R
Department of Oncology, Wayne State University School of Medicine, Detroit, USA.
Cureus. 2025 Mar 28;17(3):e81363. doi: 10.7759/cureus.81363. eCollection 2025 Mar.
A significant comorbidity of endometrial cancer is severe obesity with a Body Mass Index (BMI) of greater than 40, which can dramatically limit treatment options such as surgery or brachytherapy. Alternative treatment options need to be investigated, and in this case report, we examine a female with severe obesity and a significantly enlarged uterus who was ineligible for surgery or intracavitary brachytherapy (ICBT). She subsequently underwent treatment with external beam radiation therapy (EBRT) alone to the pelvis, followed by a stereotactic radiation therapy boost (SBRT) to the uterus. Following treatment, her uterine bleeding subsided, and she is currently without evidence of disease.
子宫内膜癌的一个显著合并症是严重肥胖，体重指数（BMI）大于40，这会极大地限制手术或近距离放射治疗等治疗选择。需要研究替代治疗方案，在本病例报告中，我们检查了一名患有严重肥胖且子宫明显增大的女性，她不符合手术或腔内近距离放射治疗（ICBT）的条件。她随后仅接受了盆腔外照射放疗（EBRT），随后对子宫进行了立体定向放射治疗强化（SBRT）。治疗后，她的子宫出血消退，目前没有疾病迹象。
