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外耳道胆脂瘤的诊断陷阱:一例病例报告的启示

Diagnostic Pitfalls of External Auditory Canal Cholesteatoma: Insights From a Case Report.

作者信息

Ramli Farid Syamil, Nasseri Zara, Abdullah Asma, Johari Mohd Hafiz, Kew Thean Yean

机构信息

Otolaryngology-Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.

Otolaryngology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.

出版信息

Cureus. 2025 Mar 25;17(3):e81200. doi: 10.7759/cureus.81200. eCollection 2025 Mar.

DOI:10.7759/cureus.81200
PMID:40291283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12022382/
Abstract

External auditory canal cholesteatoma (EACC) is a rare occurrence characterized by the keratinized mass of squamous epithelial cells in the external ear canal, leading to bone erosion and potential damage to surrounding structures. It's often misdiagnosed as otitis externa. Both conditions exhibit similar symptoms, which frequently result in misdiagnosis by clinicians. Though it is more common in older adults, EACC can occur in younger patients, as demonstrated in the case of an 18-year-old male. Insufficient diagnosis and delays in the management of this condition can result in significant complications. While the exact cause remains unclear, contributing factors may include canal trauma, chronic inflammation, or stenosis. We aim to share the experience of this pathology in order to highlight it as a differential diagnosis. This is particularly important in patients presenting with unresolved common ear symptoms.

摘要

外耳道胆脂瘤(EACC)是一种罕见病症,其特征为外耳道内鳞状上皮细胞的角质化团块,可导致骨质侵蚀并可能损害周围结构。它常被误诊为外耳道炎。这两种病症症状相似,常导致临床医生误诊。虽然EACC在老年人中更为常见,但也可发生于年轻患者,如一名18岁男性的病例所示。对该病症诊断不足和治疗延误可导致严重并发症。虽然确切病因尚不清楚,但促成因素可能包括耳道创伤、慢性炎症或狭窄。我们旨在分享这种病理学的经验,以便将其作为鉴别诊断加以强调。这在出现未缓解的常见耳部症状的患者中尤为重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b224/12022382/33f6f60791e1/cureus-0017-00000081200-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b224/12022382/4c6bcc1be4cb/cureus-0017-00000081200-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b224/12022382/5743a08e6955/cureus-0017-00000081200-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b224/12022382/33f6f60791e1/cureus-0017-00000081200-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b224/12022382/4c6bcc1be4cb/cureus-0017-00000081200-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b224/12022382/5743a08e6955/cureus-0017-00000081200-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b224/12022382/33f6f60791e1/cureus-0017-00000081200-i03.jpg

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本文引用的文献

1
External auditory canal cholesteatoma: staging and treatment strategies.外耳道胆脂瘤:分期与治疗策略
Front Neurol. 2024 Dec 19;15:1505108. doi: 10.3389/fneur.2024.1505108. eCollection 2024.
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External Auditory Canal Cholesteatoma: Clinical and Radiological Features.外耳道胆脂瘤:临床与影像学特征
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Indian J Otolaryngol Head Neck Surg. 2020 Mar;72(1):86-91. doi: 10.1007/s12070-019-01755-2. Epub 2019 Oct 31.
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TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction.Toll样受体4(TLR4)通过促进局部炎症和骨质破坏来驱动获得性胆脂瘤的发病机制。
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Therapeutic approaches to complicated cholesteatoma of the external auditory canal: a case of associated facial paresis.外耳道复杂胆脂瘤的治疗方法:一例伴面神经麻痹的病例
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