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电解质失衡及其在皮肤科应用方面的综合综述

A Comprehensive Review of Electrolyte Imbalances and Their Applied Aspects in Dermatology.

作者信息

R M KavyaDeepu, Sekar Mohnish

机构信息

Dermatology, Chettinad Hospital and Research Institute, Chennai, IND.

Dermatology, Venereology, and Leprosy, Karpaga Vinayaga Institute of Medical Sciences and Research Center, Chengalpattu, IND.

出版信息

Cureus. 2025 Mar 28;17(3):e81353. doi: 10.7759/cureus.81353. eCollection 2025 Mar.

DOI:10.7759/cureus.81353
PMID:40291321
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12034236/
Abstract

Electrolytes play a pivotal role in the maintenance of neutrality in the minerals of the cells - also, the generation and conduction of action potentials in neurons and muscles. Key electrolytes include sodium, potassium, chloride, magnesium, calcium, and phosphate. Electrolyte imbalances can result in elevated or diminished levels. Abnormal electrolyte levels, whether raised or decreased, interfere with normal physiological activities and may result in life-threatening consequences. Electrolyte imbalances are common in critical care units, although they are less frequent in dermatological conditions. Dermatologists should, however, be knowledgeable about the skin disorders and medications that are related to or may increase the risk of electrolyte imbalance to ensure that appropriate treatments are implemented immediately to avoid negative results. The objective of this review is to narrate the dermatological features of disorders involving abnormalities of sodium, potassium, calcium, phosphorus, and magnesium.

摘要

电解质在维持细胞矿物质的中性状态中起着关键作用,同时也在神经元和肌肉动作电位的产生与传导中发挥作用。关键电解质包括钠、钾、氯、镁、钙和磷酸盐。电解质失衡可导致水平升高或降低。电解质水平异常,无论是升高还是降低,都会干扰正常生理活动,并可能导致危及生命的后果。电解质失衡在重症监护病房很常见,尽管在皮肤病中不太常见。然而,皮肤科医生应该了解与电解质失衡相关或可能增加其风险的皮肤疾病和药物,以确保立即实施适当的治疗,避免不良后果。本综述的目的是阐述涉及钠、钾、钙、磷和镁异常的疾病的皮肤学特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a43/12034236/efc6bcdd1a23/cureus-0017-00000081353-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a43/12034236/efc6bcdd1a23/cureus-0017-00000081353-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a43/12034236/efc6bcdd1a23/cureus-0017-00000081353-i01.jpg

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本文引用的文献

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Incidence, Risk Factors and Prognosis of Hypokalaemia in Patients with Normokalaemia at Hospital Admission.入院时血钾正常患者低钾血症的发病率、危险因素及预后
Indian J Endocrinol Metab. 2023 Nov-Dec;27(6):537-543. doi: 10.4103/ijem.ijem_159_23. Epub 2024 Jan 11.
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GNAQ/GNA11 Mosaicism Is Associated with Abnormal Serum Calcium Indices and Microvascular Neurocalcification.GNAQ/GNA11 嵌合体与异常血清钙指数和微血管神经钙化有关。
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GNAQ/GNA11 Mosaicism Causes Aberrant Calcium Signaling Susceptible to Targeted Therapeutics.
GNAQ/GNA11 嵌合体导致钙信号异常,易受靶向治疗的影响。
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Hyperkalemia due to topical timolol for hemangioma.因局部使用噻吗洛尔治疗血管瘤导致的高钾血症。
JAAD Case Rep. 2023 Jul 17;39:53-54. doi: 10.1016/j.jdcr.2023.07.006. eCollection 2023 Sep.
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Improving diagnosis and treatment of hypomagnesemia.改善低镁血症的诊断和治疗。
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