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自闭症谱系障碍患者的音乐疗法:随机临床试验的系统评价

Music Therapy for People With Autism Spectrum Disorder: A Systematic Review of Randomized Clinical Trials.

作者信息

Alayidh Mazen, Alawad Feras, Alanazy Wateen B, Al-Harbi Fatimah O, Alotaibi Abdulelah M, Al Mohammed Qonoot A, Aljubran Abdullah S, Al-Otaibi Reem T, Al-Otaibi Raghad F, Al Rubaie Tariq R

机构信息

College of Medicine, King Khalid University, Abha, SAU.

Department of Psychiatry, Imam Abdulrahman Bin Faisal University, Dammam, SAU.

出版信息

Cureus. 2025 Mar 28;17(3):e81361. doi: 10.7759/cureus.81361. eCollection 2025 Mar.

Abstract

Autism spectrum disorder (ASD) affects social interaction, communication, and learning, with its prevalence continuing to rise, and music therapy (MT) has shown promise in improving social interactions and communication skills in individuals with ASD. This systematic review explores the relationship between ASD and music therapy, examining factors that influence its effectiveness in children. A systematic review of randomized controlled trials (RCTs) published between 2009 and 2024 was conducted to assess the effects of music therapy on children with autism. Studies were retrieved from databases such as PubMed and Google Scholar, with the final search completed by October 1, 2024, and only RCTs that evaluated music's impact on ASD and reported relevant outcomes were included, while non-RCTs, studies with a high risk of bias, and duplicates were excluded. A total of nine RCTs involving 1,327 children with ASD, aged 2-12, were analyzed; these studies assessed various music therapy interventions lasting from two weeks to eight months, with sessions occurring one to three times per week. Findings were mixed, as four studies with 449 participants reported significant improvements in social communication skills, while three larger studies with 715 participants found no significant changes in primary social outcomes but noted improvements in specific aspects of social responsiveness, and two smaller studies with 59 participants reported notable enhancements in verbal production and emotional responsiveness. Music therapy has been recognized as a beneficial intervention for improving health outcomes across various conditions, including mental health disorders, and this review highlights its potential in autism, particularly in enhancing cognitive processing, emotional responses, and social communication; however, while the findings are promising, further research with larger sample sizes and extended study durations is necessary to validate these effects.

摘要

自闭症谱系障碍(ASD)会影响社交互动、沟通和学习,其患病率持续上升,而音乐疗法(MT)已显示出有望改善ASD患者的社交互动和沟通技巧。本系统评价探讨了ASD与音乐疗法之间的关系,研究影响其对儿童有效性的因素。对2009年至2024年间发表的随机对照试验(RCT)进行了系统评价,以评估音乐疗法对自闭症儿童的影响。研究从PubMed和谷歌学术等数据库中检索,最终检索于2024年10月1日完成,仅纳入评估音乐对ASD的影响并报告相关结果的RCT,而排除非RCT、有高偏倚风险的研究和重复研究。共分析了9项涉及1327名2至12岁ASD儿童的RCT;这些研究评估了持续两周至八个月的各种音乐疗法干预措施,每周进行一至三次治疗。研究结果不一,4项涉及449名参与者的研究报告社交沟通技巧有显著改善,而3项涉及715名参与者的较大规模研究发现主要社交结果无显著变化,但指出社交反应的特定方面有所改善,2项涉及59名参与者的较小规模研究报告言语表达和情绪反应有显著增强。音乐疗法已被认为是一种有益的干预措施,可改善包括精神健康障碍在内的各种情况下的健康结果,本评价强调了其在自闭症方面的潜力,特别是在增强认知加工、情绪反应和社交沟通方面;然而,尽管研究结果很有前景,但仍需要进行更大样本量和更长研究时长的进一步研究来验证这些效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d1/12034304/a67c2d8e1b8a/cureus-0017-00000081361-i01.jpg

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