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孕期鼻科疾病:一项回顾性队列研究。

Rhinologic Conditions of Pregnancy: A Retrospective Cohort Study.

作者信息

Eltawil Yasmin, Callander Jacquelyn K, Loftus Patricia A

机构信息

University of California San Francisco School of Medicine San Francisco California USA.

Department of Otolaryngology-Head and Neck Surgery University of California, San Francisco San Francisco California USA.

出版信息

OTO Open. 2025 Apr 25;9(2):e70114. doi: 10.1002/oto2.70114. eCollection 2025 Apr-Jun.

Abstract

OBJECTIVE

To better understand the prevalence, risk factors, and management strategies of pregnancy-related rhinologic conditions.

STUDY DESIGN

Retrospective cohort study from January 2013 to January 2023.

SETTING

Tertiary level Otolaryngology-Head and Neck Surgery clinic.

METHODS

Pregnant patients with rhinologic concerns were included. Data were collected on various parameters including age during pregnancy, gestational age at evaluation for rhinologic complication, obstetric history, history of pregnancy loss, primigravida status, rhinologic condition, aspirin usage during pregnancy, and presence of advanced maternal age (AMA, ≥35 years old). Stata/SE 17.0 Software was used for statistical analysis. A -value of <.05 was considered significant.

RESULTS

Fifty-seven pregnant patients were included. Patients presented with epistaxis (N = 25, 43.9%), chronic rhinosinusitis exacerbations (N = 22, 38.6%), and rhinitis of pregnancy (N = 10, 17.5%). Mean age at presentation was 34.7 years (22-53). Multivariate analysis revealed associations between epistaxis and primigravida status ( = .008) and rhinitis of pregnancy with a history of pregnancy loss ( = .012). Gestational diabetes mellitus was significantly associated with epistaxis on univariate analysis ( = .011).

CONCLUSION

There is a need for increased awareness among health care providers, including otolaryngologists, regarding the diagnosis and management of rhinologic conditions of pregnancy.

摘要

目的

更好地了解妊娠相关鼻科疾病的患病率、危险因素及管理策略。

研究设计

2013年1月至2023年1月的回顾性队列研究。

研究地点

三级耳鼻喉头颈外科诊所。

方法

纳入有鼻科问题的孕妇。收集了各种参数的数据,包括孕期年龄、鼻科并发症评估时的孕周、产科病史、流产史、初产妇状态、鼻科疾病、孕期阿司匹林使用情况以及高龄产妇(AMA,≥35岁)的情况。使用Stata/SE 17.0软件进行统计分析。P值<0.05被认为具有统计学意义。

结果

纳入57例孕妇。患者表现为鼻出血(N = 25,43.9%)、慢性鼻窦炎加重(N = 22,38.6%)和妊娠性鼻炎(N = 10,17.5%)。就诊时的平均年龄为34.7岁(22 - 53岁)。多因素分析显示鼻出血与初产妇状态(P = 0.008)以及妊娠性鼻炎与流产史(P = 0.012)之间存在关联。单因素分析显示妊娠期糖尿病与鼻出血显著相关(P = 0.011)。

结论

包括耳鼻喉科医生在内的医疗保健提供者需要提高对妊娠相关鼻科疾病诊断和管理的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b88/12023001/24aa8d92fbd7/OTO2-9-e70114-g002.jpg

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