Lin Che-Yu, Shu Yi-Chung, Wu Wei-Ting, Chen Lan-Rong, Chang Ke-Vin
Institute of Applied Mechanics, College of Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan.
Department of Physical Medicine and Rehabilitation, Community, Geriatric Research Center, National Taiwan University Hospital, Bei-Hu Branch, Taipei, Taiwan.
Regen Ther. 2025 Apr 11;29:390-396. doi: 10.1016/j.reth.2025.03.022. eCollection 2025 Jun.
Tendon and ligament injuries remain a significant challenge for clinicians, despite considerable efforts to develop effective treatment methods. This study reviewed human studies investigating the use of platelet gel, a blood-derived biomaterial that enhances tissue healing, for treating tendon and ligament injuries. Only eight relevant articles were identified, highlighting the limited number of available studies on this topic. Of these eight articles, three reported significant positive treatment effects, two found no significant benefit, and three observed varying degrees of improvement, although not always statistically significant. Overall, six of the eight studies indicated positive effects of platelet gel based on clinical and radiographic outcomes, suggesting its potential as a promising treatment. Further clinical studies are required to confirm its efficacy and establish its role in tendon and ligament healing.
尽管人们为开发有效的治疗方法付出了巨大努力,但肌腱和韧带损伤对临床医生来说仍然是一个重大挑战。本研究回顾了关于使用血小板凝胶治疗肌腱和韧带损伤的人体研究,血小板凝胶是一种可促进组织愈合的血液衍生生物材料。仅确定了八篇相关文章,凸显了关于该主题的现有研究数量有限。在这八篇文章中,三篇报道了显著的积极治疗效果,两篇未发现显著益处,三篇观察到不同程度的改善,尽管并非总是具有统计学意义。总体而言,八项研究中有六项基于临床和影像学结果表明了血小板凝胶的积极作用,表明其作为一种有前景的治疗方法的潜力。需要进一步的临床研究来证实其疗效,并确定其在肌腱和韧带愈合中的作用。