Kasat Paschyanti, Kashikar Shivali, Parihar Pratapsingh, Sachani Pratiksha, Pradeep Utkarsh
Department of Radiodiagnosis, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Sawangi, Meghe, Wardha, India.
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Sawangi, Meghe, Wardha, India.
Radiol Case Rep. 2025 Apr 12;20(7):3271-3276. doi: 10.1016/j.radcr.2025.03.042. eCollection 2025 Jul.
Cherubism is an autosomal-dominant disorder that commonly affects young patients. Our patient a 17-year-old male presented with bilateral nontender swelling over the mandibular area and maxillary area which was insidious in onset and progressive. The diagnosis was made based on clinical and radiological features. Computed tomography of the head in bone window shows multiple lytic sclerotic expansile lesions with coarsened bony trabecular pattern giving the soap bubble appearance of bilateral mandible and maxilla. Surgical intervention was done and upon follow up patient showed drastic improvement. Based on the radiological features grading systems have been developed that help decide the management.
颌骨肥大症是一种常影响年轻患者的常染色体显性疾病。我们的患者是一名17岁男性,下颌区和上颌区出现双侧无痛性肿胀,起病隐匿且呈进行性发展。诊断基于临床和放射学特征。头颅骨窗计算机断层扫描显示多个溶骨性硬化性膨胀性病变,骨小梁模式增粗,双侧下颌骨和上颌骨呈现肥皂泡样外观。进行了手术干预,随访时患者显示出显著改善。基于放射学特征已开发出分级系统,有助于确定治疗方案。