Mousavi Khorshidi Abolhasan, Enayati Ayesheh, Behnampour Nasser, Rezaei Emadoddin, Kolangi Fatemeh
Clinical Research Development Unit [CRDU] , Sayad Shirazi Hospital, Department of Persian Medicine, School of Persian Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Ischemic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Avicenna J Phytomed. 2025 Jan-Feb;15(2):981-996. doi: 10.22038/AJP.2024.25008.
Male infertility is a common issue that affects people worldwide and presents challenges in terms of treatment. In recent times, there has been significant interest in the use of herbal remedies as a potential solution for male infertility. In this study, we aimed to assess and compare the effects of clomiphene, carrot seed, and education based on traditional Persian medicine on the sperm parameters in idiopathic male infertility.
Sixty male patients experiencing infertility were randomly divided into four groups: Clomiphene, Clomiphene + Carrot, Clomiphene + Lifestyle modification, and Clomiphene + Carrot + Lifestyle modification. In the herbal group, patients received four capsules of carrot seeds, for a total of 2 g daily for 90 days. Meanwhile, subjects in the Clomiphene group were administered one tablet of clomiphene, containing 50 mg, per day for a duration of 90 days. Sperm parameters were analyzed at the beginning and end of the study.
After the 90-day intervention, the groups that received clomiphene combined with carrot and lifestyle interventions showed significant improvements in various sperm parameters. These improvements were statistically significant compared to the control group.
The combination of carrot seeds along with clomiphene and education based on traditional Persian medicine was found to improve sperm parameters in cases of idiopathic male infertility without any adverse effects.
男性不育是一个影响全球人群的常见问题,在治疗方面存在挑战。近年来,人们对使用草药疗法作为男性不育的潜在解决方案产生了浓厚兴趣。在本研究中,我们旨在评估和比较克罗米芬、胡萝卜籽以及基于传统波斯医学的教育对特发性男性不育患者精子参数的影响。
60名不育男性患者被随机分为四组:克罗米芬组、克罗米芬+胡萝卜组、克罗米芬+生活方式改变组以及克罗米芬+胡萝卜+生活方式改变组。在草药组中,患者每天服用四粒胡萝卜籽胶囊,共2克,持续90天。同时,克罗米芬组的受试者每天服用一片含50毫克克罗米芬的片剂,持续90天。在研究开始和结束时分析精子参数。
经过90天的干预后,接受克罗米芬联合胡萝卜和生活方式干预的组在各项精子参数上有显著改善。与对照组相比,这些改善具有统计学意义。
发现胡萝卜籽与克罗米芬以及基于传统波斯医学的教育相结合,可改善特发性男性不育患者的精子参数,且无任何不良反应。