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腰椎前路椎间融合术与经椎间孔腰椎椎间融合术临床疗效的比较分析:一项长期随访研究表明,腰椎前路椎间融合术相关的相邻节段退变(ASD)发生率较低。

Comparative analysis of anterior lumbar interbody fusion and transforaminal lumbar interbody fusion in clinical outcomes: ALIF associated with lower rates of adjacent segment degeneration (ASD) in a long-term follow-up study.

作者信息

Huang Peipei, Ye Bin, Xie Fang, Zhou Jie, Tan Zhijun, Luo Zhuojing, Hu Xueyu

机构信息

Institute of Orthopedics, Xijing Hospital, The Air Force Military Medical University, Xi'an, China.

Department of Medical Statistics, The Air Force Military Medical University, Xi'an, China.

出版信息

Int Orthop. 2025 Apr 28. doi: 10.1007/s00264-025-06546-9.

Abstract

PURPOSE

To compare the long-term efficacy of anterior lumbar interbody fusion (ALIF) and posterior transforaminal lumbar interbody fusion (TLIF) in treating lumbar degenerative diseases.

METHODS

A retrospective analysis was conducted on 57 patients with lumbar degenerative diseases who underwent either ALIF or TLIF from March 2003 to October 2007. Patients were divided into an ALIF group (n = 27) and a TLIF group (n = 30). Pain was evaluated using the visual analogue scale (VAS), and the Oswestry Disability Index (ODI) was used to assess clinical outcomes. Radiographic adjacent segment degeneration (rASD) was evaluated using the Modified Pfirrmann Scale. Three-dimensional CT was used to assess the fusion rate at the last follow-up.

RESULTS

Follow-up duration ranged from 58 to 120 months, with an average of 90.6 months. No significant difference was observed in VAS and ODI scores between the two groups (P > 0.05). However, significant differences were noted before and after the operation (P < 0.05). The intervertebral disc height (IDH) and lumbar lordosis (LL) increased after the operation and during follow-ups. The IDH and LL in the ALIF group were significantly higher than those in the TLIF group both postoperatively and at follow-ups (P < 0.05). At the last follow-up, the incidence of rASD in the ALIF group was significantly lower than in the TLIF group (P < 0.05).

CONCLUSIONS

Both ALIF and TLIF provide satisfactory long-term outcomes for lumbar degenerative diseases. ALIF more effectively restores and maintains lumbar intervertebral height and lumbar lordosis, potentially reducing the incidence of adjacent segment degeneration.

摘要

目的

比较前路腰椎椎间融合术(ALIF)与后路经椎间孔腰椎椎间融合术(TLIF)治疗腰椎退行性疾病的长期疗效。

方法

对2003年3月至2007年10月期间接受ALIF或TLIF手术的57例腰椎退行性疾病患者进行回顾性分析。患者分为ALIF组(n = 27)和TLIF组(n = 30)。采用视觉模拟量表(VAS)评估疼痛,并使用Oswestry功能障碍指数(ODI)评估临床结果。使用改良的Pfirrmann量表评估影像学相邻节段退变(rASD)。在最后一次随访时使用三维CT评估融合率。

结果

随访时间为58至120个月,平均90.6个月。两组间VAS和ODI评分差异无统计学意义(P > 0.05)。然而,手术前后差异有统计学意义(P < 0.05)。术后及随访期间椎间盘高度(IDH)和腰椎前凸(LL)增加。ALIF组术后及随访时的IDH和LL均显著高于TLIF组(P < 0.05)。在最后一次随访时,ALIF组rASD的发生率显著低于TLIF组(P < 0.05)。

结论

ALIF和TLIF对腰椎退行性疾病均能提供满意的长期疗效。ALIF能更有效地恢复和维持腰椎椎间高度及腰椎前凸,可能降低相邻节段退变的发生率。

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