Poland M L, Moghissi K S, Giblin P T, Ager J W, Olson J M
Fertil Steril. 1985 Sep;44(3):396-400. doi: 10.1016/s0015-0282(16)48866-7.
Variation in semen measures was assessed bimonthly in 15 healthy men over a 6-month period. Average within-subject coefficients of variation for sperm count, morphologic features, motility, and semen volume demonstrate considerable variation. Each day of abstinence increased the volume by an increment of 0.62 ml, the count by 17.6 X 10(6)/ml, and motility by 1.2%. Sperm count and semen volume correlated positively within subjects. Intraclass and serial correlations of semen measures provided an empirical clinical guide to the number and spacing of specimens. Three specimens spaced no more than 2 weeks apart established a reliable semen profile. Findings can be applied to basic research and clinical practice.
在6个月的时间里，对15名健康男性每两个月评估一次精液指标的变化。精子计数、形态特征、活力和精液体积的平均受试者内变异系数显示出相当大的差异。禁欲的每一天会使精液体积增加0.62毫升，精子计数增加17.6×10⁶/毫升，活力增加1.2%。受试者体内精子计数与精液体积呈正相关。精液指标的组内相关和序列相关为样本数量和间隔提供了经验性临床指导。间隔不超过2周采集的3份样本可建立可靠的精液概况。研究结果可应用于基础研究和临床实践。
