Qu Yanming, Yu Jinlu
Department of Neurosurgery, Jilin City Hospital of Chemical Industry, Jilin City, China.
Department of Neurosurgery, the First Hospital of Jilin University, Changchun, China.
Medicine (Baltimore). 2025 Apr 25;104(17):e42265. doi: 10.1097/MD.0000000000042265.
Intracranial vertebral artery (VA) aneurysms are complex entities. Endovascular treatment (EVT) can be used to treat intracranial VA aneurysms. Nevertheless, managing these lesions with EVT remains challenging. Moreover, the suitability of EVT for every type of intracranial VA aneurysm has not been fully confirmed. Therefore, we conducted a needed review of the current literature and our experience summarizing the current status of and advancements in EVT in the management of intracranial VA aneurysms. In our review, several issues are discussed, including the anatomy and anomalies of the intracranial VA, the classification and natural history of intracranial VA aneurysms, indications and techniques for EVT in the management of intracranial VA aneurysms, and the outcomes of and complications experienced by patients who undergo EVT. A flowchart describing EVT options for dissecting intracranial VA aneurysms derived from the findings of this review and our experience is provided. The key to successful EVT is preservation of the posterior inferior cerebellar artery and avoidance of injury to any brainstem perforators. Currently, intracranial VA reconstruction via flow diverter deployment plays an important role in achieving successful treatment. For appropriate cases, both reconstructive and deconstructive EVT can result in good patient outcomes. However, EVT-related complications should be considered. If management of complex intracranial VA aneurysms with EVT would be expected to disproportionally harm the patient, extracranial-intracranial bypass and aneurysmectomy are often necessary. In addition, new products and techniques that show promise for achieving successful EVT in the management of intracranial VA aneurysms are described.
颅内椎动脉(VA)动脉瘤是复杂的病变。血管内治疗(EVT)可用于治疗颅内VA动脉瘤。然而,采用EVT治疗这些病变仍具有挑战性。此外,EVT对每种类型颅内VA动脉瘤的适用性尚未得到充分证实。因此,我们对当前文献及我们的经验进行了必要的回顾,总结了EVT在颅内VA动脉瘤治疗中的现状和进展。在我们的回顾中,讨论了几个问题,包括颅内VA的解剖结构和异常情况、颅内VA动脉瘤的分类和自然病程、EVT治疗颅内VA动脉瘤的适应证和技术,以及接受EVT治疗的患者的治疗结果和并发症。提供了一个根据本次回顾结果和我们的经验得出的用于治疗颅内VA夹层动脉瘤的EVT选择流程图。成功进行EVT的关键是保留小脑后下动脉并避免损伤任何脑干穿支血管。目前,通过血流导向装置进行颅内VA重建在实现成功治疗中发挥着重要作用。对于合适的病例,重建性和去构造性EVT均可使患者获得良好的治疗结果。然而,应考虑与EVT相关的并发症。如果预期采用EVT治疗复杂颅内VA动脉瘤会对患者造成不成比例的伤害,则通常需要进行颅外-颅内搭桥术和动脉瘤切除术。此外,还介绍了有望在颅内VA动脉瘤治疗中实现成功EVT的新产品和新技术。