Vidnes J, Finne H
Biol Neonate. 1977;31(1-2):1-6. doi: 10.1159/000240934.
Immunoreactive insulin was measured in amniotic fluid from Rh-immunized women (anti-D antibody). The degree of immunization was expressed by the spectrophotometric index of the amniotic fluid and by the capillary hemoglobin concentration of the newborn. Higher levels of insulin were found in amniotic fluid from severely Rh-immunized mothers than from non-immunized, and a correlation between the degree of immunization and insulin concentration was indicated. To our knowledge this has not previously been demonstrated, and may justify some new hypotheses concerning the pathogenesis of the observed higher frequency of hyperinsulinism in babies of Rh-immunized mothers.
在Rh免疫（抗-D抗体）女性的羊水中检测免疫反应性胰岛素。免疫程度通过羊水的分光光度指数和新生儿的毛细血管血红蛋白浓度来表示。与未免疫的母亲相比，严重Rh免疫母亲的羊水中胰岛素水平更高，且表明免疫程度与胰岛素浓度之间存在相关性。据我们所知，此前尚未有过此类证明，这可能为关于Rh免疫母亲所生婴儿中观察到的高胰岛素血症频率较高的发病机制的一些新假设提供依据。
