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外伤后五十年虹膜植入囊肿生长

Iris implantation cysts growth five decades after trauma.

作者信息

Englisch Colya N, Boden Karl T, Rudolph Clemens N, Semoulin Charlotte, Szurman Peter, Wakili Philip

机构信息

Eye Clinic Sulzbach, Knappschaft Hospitals, 66280 Sulzbach/Saar, Germany.

Institute of Experimental Ophthalmology, Saarland University, 66421, Homburg, Germany.

出版信息

Am J Ophthalmol Case Rep. 2025 Apr 11;38:102333. doi: 10.1016/j.ajoc.2025.102333. eCollection 2025 Jun.

Abstract

PURPOSE

Implantation cysts of the iris are rare benign lesions resulting from epithelial downgrowth after trauma or surgery. This report highlights the management of an exceptional case of implantation cysts manifestation five decades after penetrating childhood trauma.

OBSERVATION

A 59-year-old male patient with a history of penetrating trauma of the cornea at the age of 4 years presented with cystic anterior chamber lesions exhibiting pigment deposition. The pupil was distorted and almost entirely covered. 50 MHz ultrasound biomicroscopy and anterior segment optical coherence tomography displayed no evidence of malignancy. The cystic lesions were excised in an endothelium-protective manner and histopathological analysis revealed dysplasia-free corneal squamous epithelium compatible with implantation cysts of the iris.

CONCLUSION AND IMPORTANCE

Implantation cysts of the iris are benign and rare. Anterior segment imaging is required to exclude malignancies. Most cases emerge after surgery or trauma within months to a few years after injury. However, occurrence can also be delayed by several decades. It is thus mandatory to demand a full and long-lasting ophthalmological anamnesis, to accurately distinguish, diagnose, and treat cystic lesions of the iris.

摘要

目的

虹膜植入囊肿是创伤或手术后上皮细胞内生导致的罕见良性病变。本报告重点介绍了一例特殊病例的处理情况,该病例为儿童期穿透性创伤五十年后出现的虹膜植入囊肿表现。

观察

一名59岁男性患者,4岁时曾有角膜穿透伤病史,现出现伴有色素沉着的囊性前房病变。瞳孔变形且几乎完全被覆盖。50兆赫超声生物显微镜检查和眼前节光学相干断层扫描未显示恶性迹象。以保护内皮的方式切除了囊性病变,组织病理学分析显示角膜鳞状上皮无发育异常,符合虹膜植入囊肿。

结论与意义

虹膜植入囊肿是良性且罕见的。需要进行眼前节成像以排除恶性病变。大多数病例在手术或创伤后数月至数年出现。然而,发病也可能延迟数十年。因此,必须详细询问完整且长期的眼科病史,以准确区分、诊断和治疗虹膜囊性病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a2e/12036079/e239362776df/gr1.jpg

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