Côté-Corriveau Gabriel, Silva-Lavigne Nicole, Maigné Méloë, Ayoub Aimina, Luu Thuy Mai, Drouin Olivier, Auger Nathalie
Department of Pediatrics, Sainte Justine Hospital Research Centre, University of Montreal, Montreal, QC, Canada.
Institut national de santé publique du Québec, Montreal, QC, Canada.
Public Health Rep. 2025 Apr 29:333549251314304. doi: 10.1177/00333549251314304.
The health status of Middle Eastern or North African (MENA) populations in Western countries is poorly understood. We assessed whether MENA infants and mothers have a greater risk of adverse pregnancy and birth outcomes than non-MENA infants and mothers in Quebec, Canada.
We conducted a population-based observational study of 809 172 infants born to pregnant women in Quebec from 2008 through 2020. We identified infants in the MENA group based on self-reported mother tongue (Arabic or Turkish) and parents' country of birth (North African or Middle Eastern country). We compared infant and maternal outcomes, including gestational diabetes, cesarean delivery, preterm birth, severe maternal or neonatal morbidity, and other pregnancy and birth complications between the MENA and non-MENA groups. Using log-binomial regression models, we calculated risk ratios (RRs) and 95% CIs to measure the risk of adverse pregnancy and birth outcomes for the MENA group compared with the non-MENA group, adjusting for maternal age, comorbidity, and other patient characteristics.
Compared with the non-MENA group (n = 716 387), the MENA group (n = 92 785) had an elevated risk of gestational diabetes (RR = 1.51; 95% CI, 1.48-1.55), postterm birth (RR = 1.24; 95% CI, 1.08-1.42), and short-stay neonatal intensive care unit admission (RR = 1.91; 95% CI, 1.82-1.99). However, MENA infants were 15% to 50% less likely than non-MENA infants to be born preterm, have severe neonatal morbidity, and have a mother with preeclampsia or severe maternal morbidity.
Although findings among MENA infants and mothers in Quebec were reassuring overall, MENA infants and mothers may benefit from closer perinatal follow-up to improve complications of gestational diabetes.
西方国家中东或北非(MENA)人群的健康状况鲜为人知。我们评估了MENA地区的婴儿和母亲与加拿大魁北克非MENA地区的婴儿和母亲相比,是否有更高的不良妊娠和分娩结局风险。
我们对2008年至2020年在魁北克的孕妇所生的809172名婴儿进行了一项基于人群的观察性研究。我们根据自我报告的母语(阿拉伯语或土耳其语)和父母的出生国家(北非或中东国家)确定MENA组中的婴儿。我们比较了MENA组和非MENA组之间的婴儿和母亲结局,包括妊娠期糖尿病、剖宫产、早产、严重的母亲或新生儿发病率以及其他妊娠和分娩并发症。使用对数二项回归模型,我们计算了风险比(RRs)和95%置信区间(CIs),以衡量MENA组与非MENA组相比不良妊娠和分娩结局的风险,并对母亲年龄、合并症和其他患者特征进行了调整。
与非MENA组(n = 716387)相比,MENA组(n = 92785)患妊娠期糖尿病(RR = 1.51;95% CI,1.48 - 1.55)、过期产(RR = 1.24;95% CI,1.08 - 1.42)和入住短期新生儿重症监护病房(RR = 1.91;95% CI,1.82 - 1.99)的风险更高。然而,MENA地区的婴儿比非MENA地区的婴儿早产、患严重新生儿疾病以及母亲患先兆子痫或严重母亲疾病的可能性低15%至50%。
尽管魁北克MENA地区婴儿和母亲的总体研究结果令人放心,但MENA地区的婴儿和母亲可能受益于更密切的围产期随访,以改善妊娠期糖尿病的并发症。