Kittel-Schneider Sarah
Department of Psychiatry and Neurobehavioural Science, Acute Adult Mental Health Unit, Cork University Hospital, University College Cork, T12DC4A, Wilton, Cork, Irland.
APC Microbiome, University College of Cork, Cork, Irland.
Nervenarzt. 2025 May;96(3):309-317. doi: 10.1007/s00115-025-01828-4. Epub 2025 Apr 29.
There is a close connection throughout the lifespan between attention deficit/hyperactivity disorder (ADHD) and an increased risk of cardiometabolic diseases, such as obesity, diabetes mellitus and arterial hypertension. According to current knowledge, the causes are genetic factors, dopamine metabolism disorders, circadian rhythm disorders, inflammatory processes and, last but not least, an unhealthy lifestyle. The treatment of individuals with ADHD and comorbid cardiometabolic diseases requires an individualized approach with lifestyle changes, psychotherapy and pharmacotherapy, taking possible cardiometabolic side effects of the ADHD medication into account.
在整个生命周期中,注意力缺陷多动障碍(ADHD)与肥胖、糖尿病和动脉高血压等心脏代谢疾病风险增加之间存在密切联系。根据目前的认知,其病因包括遗传因素、多巴胺代谢紊乱、昼夜节律紊乱、炎症过程,以及最后但同样重要的不健康生活方式。对患有ADHD和合并心脏代谢疾病的个体进行治疗,需要采取个性化方法,包括生活方式改变、心理治疗和药物治疗,并考虑到ADHD药物可能产生的心脏代谢副作用。