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嘌呤霉素氨基核苷肾病中35硫酸盐掺入肾小球基底膜的情况。

Incorporation of 35sulfate into the glomerular basement membrane in puromycin aminonucleoside nephrosis.

作者信息

Garin E H, Boggs K P, Burke F C

出版信息

Int J Pediatr Nephrol. 1985 Apr-Jun;6(2):117-20.

PMID:4030221
Abstract

The in vitro incorporation of 35sulfate into the glomerular basement membrane (GBM) of rats with puromycin aminonucleoside was compared with that of normal rats. 35Sulfate incorporation into the GBM of glomeruli from nephrotic rats did not differ significantly from that observed in normal rats. These data suggest that 35sulfate anionic charges in the GBM play no important role in the pathogenesis of the proteinuria in this experimental model.

摘要

将嘌呤霉素氨基核苷诱导的大鼠肾小球基底膜(GBM)中35硫酸盐的体外掺入情况与正常大鼠进行了比较。肾病大鼠肾小球GBM中35硫酸盐的掺入与正常大鼠中观察到的情况相比无显著差异。这些数据表明,GBM中的35硫酸盐阴离子电荷在该实验模型蛋白尿的发病机制中不起重要作用。

相似文献

1
Incorporation of 35sulfate into the glomerular basement membrane in puromycin aminonucleoside nephrosis.嘌呤霉素氨基核苷肾病中35硫酸盐掺入肾小球基底膜的情况。
Int J Pediatr Nephrol. 1985 Apr-Jun;6(2):117-20.
2
Glomerular basement membrane heparan sulfate glycosaminoglycan in aminonucleoside of puromycin nephrosis.嘌呤霉素氨基核苷肾病中的肾小球基底膜硫酸乙酰肝素糖胺聚糖
Child Nephrol Urol. 1988;9(3):121-6.
3
Laminin in glomerular basement membranes of aminonucleoside nephrotic rats. Increased proteinuria induced by antilaminin immunoglobulin G.氨基核苷肾病大鼠肾小球基底膜中的层粘连蛋白。抗层粘连蛋白免疫球蛋白G诱导蛋白尿增加。
Lab Invest. 1983 Jul;49(1):38-47.
4
Anionic site and immunogold quantitation of heparan sulfate proteoglycans in glomerular basement membranes of puromycin aminonucleoside nephrotic rats.嘌呤霉素氨基核苷肾病大鼠肾小球基底膜中硫酸乙酰肝素蛋白聚糖的阴离子位点及免疫金定量分析
Anat Rec. 1991 Sep;231(1):35-47. doi: 10.1002/ar.1092310106.
5
Alterations in proteoglycan metabolism in the nephrotic syndrome induced by the aminonucleoside of puromycin.嘌呤霉素氨基核苷诱导的肾病综合征中蛋白聚糖代谢的改变。
Lab Invest. 1984 May;50(5):543-51.
6
Modulation of basement membrane component gene expression in glomeruli of aminonucleoside nephrosis.氨基核苷肾病肾小球中基底膜成分基因表达的调节
Lab Invest. 1991 May;64(5):640-7.
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Altered expression of NDST-1 messenger RNA in puromycin aminonucleoside nephrosis.嘌呤霉素氨基核苷肾病中NDST-1信使核糖核酸的表达改变
J Lab Clin Med. 2004 Feb;143(2):106-14. doi: 10.1016/j.lab.2003.10.012.
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Cyclosporin reduces proteinuria in rats with aminonucleoside nephrosis.环孢素可降低氨基核苷肾病大鼠的蛋白尿。
J Pathol. 1992 Mar;166(3):297-301. doi: 10.1002/path.1711660313.
9
Effect of aminonucleoside nephrosis on immune complex localization in autologous immune complex nephropathy in rats.氨基核苷肾病对大鼠自身免疫复合物性肾病中免疫复合物定位的影响。
J Clin Invest. 1978 Mar;61(3):561-72. doi: 10.1172/JCI108967.
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Glomerular tumor necrosis factor and interleukin 1 during acute aminonucleoside nephrosis. An immunohistochemical study.急性氨基核苷肾病时肾小球肿瘤坏死因子和白细胞介素1。一项免疫组织化学研究。
Lab Invest. 1991 Jan;64(1):21-8.