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Incidence of acute Charcot foot in patients with diabetes.

作者信息

Ahmed Osman Heider, Winther-Jensen Matilde, Svendsen Ole Lander

机构信息

Department of Endocrinology, Copenhagen Diabetes Foot Center (CODIF).

Center for Clinical Research and Prevention, Section for Data, Biostatistics, and Pharmacoepidemiology, Copenhagen University Hospital - Bispebjerg and Frederiksberg Hospital.

出版信息

Dan Med J. 2025 Mar 25;72(4):A08240556. doi: 10.61409/A08240556.

Abstract

INTRODUCTION

Acute Charcot foot is a rare but serious complication of diabetes mellitus. With improved diabetes treatment, the annual incidence of acute Charcot foot may have decreased. This study aimed to investigate the annual incidence and incidence rate of acute Charcot foot in patients with an ICD diagnosis code of diabetes in Denmark from 2000 to 2021. Furthermore, the analyses included differences between the five Danish regions. Finally, the impact of the COVID-19 pandemic and the nurses' strike in the summer of 2021 in Denmark was also examined.

METHODS

This was a register-based study conducted in Denmark from 2000 to 2021. Nation-wide and regional, annual incidence and incidence rates of acute Charcot foot were calculated. Kendall's tau was used to test changes in incidence rates.

RESULTS

A significant increase was found in the annual incidence of acute Charcot foot with a correlation of 0.6 (p less-than 0.0005) together with a decline in the annual incidence rate of acute Charcot foot (correlation of -0.6 with p = 0.0005). No differences were observed between theDanish regions. No change in acute Charcot foot incidence rate among diabetes patients was found during 2018-2021 (correlation of 0.3; p = 0.5).

CONCLUSION

The annual incidence increased, whereas the annual incidence rate of acute Charcot foot in patients with an ICD diagnosis code of diabetes in Denmark declined during 2000-2021, with no significant regional differences or change during the COVID-19 and nurses' strike.

FUNDING

None.

TRIAL REGISTRATION

Not relevant.

摘要

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