Khattab Mostafa S A, Haiqiang Li, Shaoxun Tang, Qiongxian Yan, Yong Liu, Zhiliang Tan, Qi Lu
State Key Laboratory of Forage Breeding-by-Design and Utilization, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, and Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, China.
Dairy Department, National Research Centre, Giza, Egypt.
Front Vet Sci. 2025 Apr 15;12:1503487. doi: 10.3389/fvets.2025.1503487. eCollection 2025.
The present study explored the immune response, milk production and health status of mastitis-infected lactating cows fed diets supplemented with Macleaya cordata extract.
Twenty-four Holstein and Jersey cows were equally assigned to two experimental groups: the first group was fed a control diet (control), and the second experimental group was fed a control diet plus Macleaya extract at 8 g/head/d (Macleaya). The experiment was conducted for 60 days. The daily milk yield was recorded, and the milk samples were analyzed for total solids, fat, protein, and lactose contents.
Blood samples were analyzed for different blood constituents, biochemical parameters, antioxidant capacity and immune indices. Compared with the control, the addition of Macleaya improved immune indices ( < 0.05). No significant differences ( > 0.05) were recorded between the two groups for different rumen liquor parameters, antioxidant capacities, milk yields or compositions. However, supplementing the diet with Macleaya significantly decreased SCC, SAA, and endotoxin.
This study suggested that supplementing the diets of lactating cows with Macleaya extract potentially improved their immune competence without adversely impacting their productive performance.
本研究探讨了在感染乳腺炎的泌乳奶牛日粮中添加博落回提取物后，奶牛的免疫反应、产奶量和健康状况。
将24头荷斯坦奶牛和泽西奶牛平均分为两个实验组：第一组饲喂对照日粮（对照组），第二实验组在对照日粮基础上，每头每天添加8克博落回提取物（博落回组）。实验持续60天。记录每日产奶量，并对牛奶样本进行总固体、脂肪、蛋白质和乳糖含量分析。
对血样进行不同血液成分、生化参数、抗氧化能力和免疫指标分析。与对照组相比，添加博落回可改善免疫指标（<0.05）。两组在不同瘤胃液参数、抗氧化能力、产奶量或组成方面无显著差异（>0.05）。然而，在日粮中添加博落回可显著降低体细胞计数、血清淀粉样蛋白A和内毒素。
本研究表明，在泌乳奶牛日粮中添加博落回提取物可能提高其免疫能力，而不会对其生产性能产生不利影响。
