Hattori Yusuke, Usami Takuya, Kuroyanagi Gen, Iwata Hidetoshi, Sekiya Isato, Nagaya Waguri-Yuko, Murakami Hideki, Takada Naoya
Orthopaedic Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, JPN.
Rehabilitation Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, JPN.
Cureus. 2025 Mar 30;17(3):e81448. doi: 10.7759/cureus.81448. eCollection 2025 Mar.
This study aimed to investigate the effect of hydroxyapatite (HA) augmentation on the maximum lag screw insertion torque (T) using extracted human femoral heads.
Hemispherical femoral heads extracted from patients who underwent bipolar hip arthroplasty were used. These samples were divided into the HA treatment group (HA group) and the non-HA treatment group (N group). After drilling, HA was inserted into the femoral heads in the HA group. A lag screw was inserted into the femoral head using a dedicated jig in both groups. The bone mineral density of the uninjured contralateral femoral neck (f-BMD), T, and the T/f-BMD ratio were evaluated.
Twenty-seven samples were analyzed in this study: 14 samples in the HA group and 13 samples in the N group. No significant differences were observed in f-BMD and T between the two groups (HA: 0.49 ± 0.11 vs. N: 0.48 ± 0.092 g/cm, p = 0.90; HA: 5.6 ± 1.9 vs. N: 4.3 ± 1.9 N･m, p = 0.78). Considering bone mineral density, the HA group showed a significantly higher T/f-BMD ratio than the N group (11.7 ± 3.3 vs. 8.9 ± 3.2 N･m･cm/g, p = 0.036). Correlation coefficients between f-BMD and Tin both groups were moderately strong (r = 0.50 vs. 0.50).
Our results suggest that HA augmentation improves lag screw fixation strength in the treatment of osteoporotic intertrochanteric femoral fractures.
本研究旨在使用提取的人类股骨头，研究羟基磷灰石（HA）增强对最大拉力螺钉插入扭矩（T）的影响。
使用从接受双极髋关节置换术的患者中提取的半球形股骨头。这些样本被分为HA治疗组（HA组）和非HA治疗组（N组）。钻孔后，将HA插入HA组的股骨头中。两组均使用专用夹具将拉力螺钉插入股骨头。评估未受伤对侧股骨颈的骨矿物质密度（f-BMD）、T以及T/f-BMD比值。
本研究共分析了27个样本：HA组14个样本，N组13个样本。两组之间的f-BMD和T均未观察到显著差异（HA组：0.49±0.11 vs. N组：0.48±0.092 g/cm，p = 0.90；HA组：5.6±1.9 vs. N组：4.3±1.9 N·m，p = 0.78）。考虑骨矿物质密度，HA组的T/f-BMD比值显著高于N组（11.7±3.3 vs. 8.9±3.2 N·m·cm/g，p = 0.036）。两组中f-BMD与T之间的相关系数均为中等强度（r = 0.50 vs. 0.50）。
我们的结果表明，HA增强可提高骨质疏松性股骨转子间骨折治疗中拉力螺钉的固定强度。
