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在不稳定型股骨颈骨折中,螺钉 - 锚定固定系统的骨水泥强化是否更具优势?一项生物力学尸体研究。

Is bone-cement augmentation of screw-anchor fixation systems superior in unstable femoral neck fractures? A biomechanical cadaveric study.

作者信息

Knobe Matthias, Bettag Sebastian, Kammerlander Christian, Altgassen Simon, Maier Klaus-Jürgen, Nebelung Sven, Prescher Andreas, Horst Klemens, Pishnamaz Miguel, Herren Christian, Mundt Marion, Stoffel Marcus, Markert Bernd, Gueorguiev Boyko

机构信息

Department of Orthopaedic Trauma, University of Aachen Medical Center, Germany.

Department for General, Trauma and Reconstructive Surgery, Ludwig Maximilian University Munich, Munich, Germany.

出版信息

Injury. 2019 Feb;50(2):292-300. doi: 10.1016/j.injury.2018.10.038. Epub 2018 Oct 30.

Abstract

OBJECTIVES

Improved fixation techniques with optional use of bone cements for implant augmentation have been developed to enhance stability and reduce complication rates after osteosynthesis of femoral neck fractures. This biomechanical study aimed to evaluate the effect of cement augmentation on implant anchorage and overall performance of screw-anchor fixation systems in unstable femoral neck fractures.

METHODS

Ten pairs of human cadaveric femora were used to create standardized femoral neck fractures (Pauwels type 3 fractures; AO/OTA 31-B2) with comminution and were fixed by means of a rotationally stable screw-anchor (RoSA) system. The specimens were assigned pairwise to two groups and either augmented with PMMA-based cement (Group 1, augmented) or left without such augmentation (Group 2, control). Biomechanical testing, simulating physiological loading at four distinct load levels, was performed over 10.000 cycles for each level with the use of a multidimensional force-transducer system. Data was analysed by means of motion tracking.

RESULTS

Stiffness, femoral head rotation, implant migration, femoral neck shortening, and failure load did not differ significantly between the two groups (p ≥ .10). For both groups, the main failure type was dislocation in the frontal plane with consecutive varus collapse). In the cement-augmented specimens, implant migration and femoral neck shortening were significantly dependent on bone mineral density (BMD), with higher values in osteoporotic bones. There was a correlation between failure load and BMD in cement-augmented specimens.

CONCLUSION

In screw-anchor fixation of unstable femoral neck fractures, bone-cement augmentation seems to show no additional advantages in regard to stiffness, rotational stability, implant migration, resistance to fracture displacement, femoral neck shortening or failure load.

摘要

目的

已开发出改进的固定技术,可选择性地使用骨水泥进行植入物增强,以提高稳定性并降低股骨颈骨折骨合成后的并发症发生率。本生物力学研究旨在评估骨水泥增强对不稳定股骨颈骨折中植入物锚固和螺钉锚固固定系统整体性能的影响。

方法

使用十对人体尸体股骨制造具有粉碎的标准化股骨颈骨折( Pauwels 3型骨折;AO/OTA 31-B2),并通过旋转稳定的螺钉锚固(RoSA)系统进行固定。将标本成对分配到两组,一组用基于PMMA的骨水泥增强(第1组,增强组),另一组不进行此类增强(第2组,对照组)。使用多维力传感器系统在四个不同负荷水平模拟生理负荷进行生物力学测试,每个水平进行10000次循环。通过运动跟踪分析数据。

结果

两组之间的刚度、股骨头旋转、植入物迁移、股骨颈缩短和破坏负荷没有显著差异(p≥0.10)。两组的主要失效类型均为额面脱位并伴有连续内翻塌陷。在骨水泥增强的标本中,植入物迁移和股骨颈缩短显著依赖于骨矿物质密度(BMD),骨质疏松骨中的值更高。骨水泥增强标本的破坏负荷与BMD之间存在相关性。

结论

在不稳定股骨颈骨折的螺钉锚固固定中,骨水泥增强在刚度、旋转稳定性、植入物迁移、抗骨折移位、股骨颈缩短或破坏负荷方面似乎没有额外优势。

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