Wei Feng, Jiang Xiaoning, He Dalin, Wang Qianqian, Diao Youxiang, Tang Yi
College of Animal Science and Technology, Shandong Agricultural University, 61 Daizong Street, Tai'an, Shandong Province 271018, China.
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Tai'an, Shandong 271018, China.
Transbound Emerg Dis. 2023 Apr 24;2023:8515116. doi: 10.1155/2023/8515116. eCollection 2023.
Goose astrovirus genotype 2 (GoAstV2), as a contagious pathogen of fatal visceral gout in goslings, has been widely distributed in major goose-producing regions in China since 2017, leading to significant economic losses to the Chinese goose industry. In this study, a novel goose astrovirus (GoAstV-SDHZ) was isolated and identified from laying hens with nephritis for the first time. Phylogenetic analysis of the sequenced genome of ORF2 gene revealed that the GoAstV-SDHZ strain clustered into Group 2 GoAstVs and shared the highest identity with the other representative GoAstV2 in the nucleotide (ORF1a: 97.2-99.7%; ORF1b: 98.4-99.8%; ORF2: 97.2-99.9%) and amino acid sequence (ORF1a: 98.2-100%; ORF1b: 98.8-99.6%; ORF2: 97.4-99.6%). In summary, this study provides the first evidence of the GoAstV2 infection in Chinese laying hens, which raises potential threat to the poultry industry in China.
鹅星状病毒2型（GoAstV2）作为雏鹅致命性内脏痛风的一种传染性病原体，自2017年以来已在中国主要养鹅地区广泛传播，给中国养鹅业造成了重大经济损失。在本研究中，首次从患有肾炎的蛋鸡中分离并鉴定出一种新型鹅星状病毒（GoAstV-SDHZ）。对ORF2基因测序基因组的系统发育分析表明，GoAstV-SDHZ毒株聚类到2型鹅星状病毒组，并且在核苷酸（ORF1a：97.2-99.7%；ORF1b：98.4-99.8%；ORF2：97.2-99.9%）和氨基酸序列（ORF1a：98.2-100%；ORF1b：98.8-99.6%；ORF2：97.4-99.6%）方面与其他代表性GoAstV2具有最高的同源性。总之，本研究提供了中国蛋鸡感染GoAstV2的首个证据，这对中国家禽业构成了潜在威胁。
