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儿童自身免疫性胰腺炎:一例报告

Autoimmune Pancreatitis in Children: A Case Report.

作者信息

Hendlisz Barbara, Dirckx Amélie, Cassart Marie, Lê Phu Quoc

机构信息

Pediatrics Department, Hôpitaux Iris-Sud, Brussels, Belgium.

Radiology Department, Hôpitaux Iris-Sud, Brussels, Belgium.

出版信息

Case Rep Gastroenterol. 2025 Apr 29;19(1):303-312. doi: 10.1159/000544785. eCollection 2025 Jan-Dec.

Abstract

INTRODUCTION

Autoimmune pancreatitis (AIP) is a rare and distinct condition in children compared to adults. Despite being based on adult diagnostic criteria, several differences have been reported, making pediatric AIP a challenging diagnosis.

CASE PRESENTATION

A 14-year-old adolescent presented to the emergency department with abdominal pain, vomiting, and jaundice. A combination of biological and radiological assessments led to the diagnosis of AIP. The patient experienced a swift and complete recovery without intensive treatment.

CONCLUSION

AIP in children is an intriguing diagnosis and should be considered when a child presents with abdominal pain, vomiting, and jaundice. The natural history and pathophysiology of the disease are still uncertain. Specific markers for the disease need to be established. Studies on larger sample sizes are necessary to address these questions and improve AIP diagnosis and management.

摘要

引言

与成人相比,自身免疫性胰腺炎(AIP)在儿童中是一种罕见且独特的病症。尽管基于成人诊断标准,但已有多项差异被报道,这使得儿童AIP的诊断具有挑战性。

病例报告

一名14岁青少年因腹痛、呕吐和黄疸就诊于急诊科。生物和放射学评估相结合得出了AIP的诊断。该患者未经强化治疗即迅速完全康复。

结论

儿童AIP是一个引人关注的诊断,当儿童出现腹痛、呕吐和黄疸时应予以考虑。该疾病的自然史和病理生理学仍不确定。需要确立该疾病的特异性标志物。有必要开展更大样本量的研究来解决这些问题并改善AIP的诊断和管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53bc/12040306/d129c87108d0/crg-2025-0019-0001-544785_F01.jpg

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