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6只犬的葡萄膜炎伴白发症和白癜风

Uveitis associated with poliosis and vitiligo in six dogs.

作者信息

Kern T J, Walton D K, Riis R C, Manning T O, Laratta L J, Dziezyc J

出版信息

J Am Vet Med Assoc. 1985 Aug 15;187(4):408-14.

PMID:4030476
Abstract

Idiopathic panuveitis with retinal detachment was associated with facial poliosis, vitiligo, and alopecia in 6 dogs; 4 were adult males. Dermatohistologic examination of affected facial sites from all dogs revealed a lichenoid dermatitis and unusual histiocytic cells. Intensive topical and systemic corticosteroid and topical mydriatic/cycloplegic therapy was successful in controlling uveitis in all dogs for variable periods. Three dogs, monitored for 12, 30, and 46 months, retained useful vision despite infrequent recurrence of uveitis. One dog was lost for subsequent examination. Two dogs were euthanatized and necropsied. Ocular histologic examination of these dogs revealed extensive granulomatous iridocyclitis and choroiditis, with retinal detachment and lenticular degeneration.

摘要

6只犬的特发性全葡萄膜炎伴视网膜脱离与面部毛发变白、白癜风和脱发有关;4只为成年雄性犬。对所有犬受影响面部部位进行的皮肤组织学检查显示为苔藓样皮炎和异常组织细胞。强化局部和全身使用皮质类固醇以及局部使用散瞳/睫状肌麻痹剂治疗成功地在不同时间段控制了所有犬的葡萄膜炎。3只分别监测了12个月、30个月和46个月的犬,尽管葡萄膜炎偶尔复发,但仍保留了有用视力。1只犬失访以便后续检查。2只犬实施安乐死并进行了尸检。对这些犬的眼部组织学检查显示广泛的肉芽肿性虹膜睫状体炎和脉络膜炎,伴有视网膜脱离和晶状体变性。

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引用本文的文献

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Uveodermatological syndrome in dogs: A review of diagnosis, management, and ophthalmic patient needs.犬葡萄膜皮肤综合征:诊断、治疗及眼科患者需求综述
Vet Med (Praha). 2025 Jun 25;70(6):185-195. doi: 10.17221/10/2025-VETMED. eCollection 2025 Jun.
2
Polyautoimmunity manifest as inflammatory myopathy, uveitis, and progressive cutaneous depigmentation in a mixed breed dog: a case report.多器官自身免疫病表现为混合品种犬的炎性肌病、葡萄膜炎和进行性皮肤色素脱失:病例报告。
BMC Vet Res. 2023 Oct 10;19(1):198. doi: 10.1186/s12917-023-03764-4.
3
Autoimmune diseases affecting skin melanocytes in dogs, cats and horses: vitiligo and the uveodermatological syndrome: a comprehensive review.
自身免疫性疾病影响犬、猫和马的皮肤黑素细胞:白癜风和眼皮肤综合征:全面综述。
BMC Vet Res. 2019 Jul 19;15(1):251. doi: 10.1186/s12917-019-2003-9.
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Ocular pathology in melanomatous Sinclair miniature swine.黑素瘤性辛克莱小型猪的眼部病理学
Am J Pathol. 1988 Apr;131(1):62-72.