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从呼吸困难到更好生活:通过居家肺康复改善慢性阻塞性肺疾病护理

From Breathlessness to Better Living: Transforming COPD Care with Home-based Pulmonary Rehabilitation.

作者信息

Kasim Abins Thozhuthinkal, Gaur Ravi, Gonnade Nitesh Manohar, Sheenam Nagma, Kolakkanni Chinchu, Ganesan Sarankumar, Kannan Adharshna Thangamalai

机构信息

Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, Nagpur, Maharashtra, India.

出版信息

Rambam Maimonides Med J. 2025 Apr 29;16(2):e0008. doi: 10.5041/RMMJ.10543.

Abstract

BACKGROUND

Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD), significantly impact patients' quality of life by limiting physical function, mobility, and overall well-being. Pulmonary rehabilitation (PR), particularly home-based programs, has emerged as a vital non-pharmacological intervention to address these limitations. However, comprehensive assessments of the impact of home-based PR on both lung function and disability in COPD patients remain limited.

OBJECTIVE

This study aimed to evaluate the effectiveness of a 12-week home-based PR program on pulmonary function and disability in COPD patients, using pulmonary function tests (PFTs) and the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) to assess outcomes across multiple domains.

METHODS

A prospective, single-arm pre-post interventional study was conducted among 62 COPD patients at All India Institute of Medical Sciences, Jodhpur. Participants completed a 12-week home-based PR program, which included endurance exercises, breathing techniques, and self-management education. Pulmonary function tests were conducted, and disability levels were assessed using WHODAS 2.0 at baseline and after completing the program.

RESULTS

Improvements were observed in pulmonary function, with forced vital capacity (FVC), and forced expiratory volume in one second (FEV1), showing substantial increases (FVC: 2.50±0.43 L to 2.85±0.59 L; FEV1: 1.53±0.33 L to 1.63±0.34 L; P<0.001). The WHODAS 2.0 scores demonstrated notable reductions in disability, particularly in the life activities and participation domains (P<0.001). Cognitive and self-care scores remained stable, while improvements in mobility were observed but not significant. Regression analysis revealed a strong negative correlation between increases in FVC and reductions in WHODAS 2.0 total scores (r=-0.65), highlighting FVC as a key predictor of disability reduction.

CONCLUSION

The 12-week home-based PR program improved lung function and reduced disability in COPD patients. These findings support the role of home-based PR as a viable, patient-centered alternative to traditional rehabilitation, addressing both physical and social dimensions of health. Future research should focus on long-term outcomes, the potential for broader implementation, and expanding access to underserved populations.

摘要

背景

慢性呼吸系统疾病,如慢性阻塞性肺疾病(COPD),通过限制身体功能、活动能力和整体健康状况,对患者的生活质量产生重大影响。肺康复(PR),特别是居家康复项目,已成为解决这些限制的重要非药物干预措施。然而,对于居家PR对COPD患者肺功能和残疾影响的全面评估仍然有限。

目的

本研究旨在评估一项为期12周的居家PR项目对COPD患者肺功能和残疾状况的有效性,使用肺功能测试(PFTs)和世界卫生组织残疾评估量表2.0(WHODAS 2.0)来评估多个领域的结果。

方法

在焦特布尔全印度医学科学研究所对62例COPD患者进行了一项前瞻性、单臂干预前后研究。参与者完成了一项为期12周的居家PR项目,其中包括耐力训练、呼吸技巧和自我管理教育。在基线和完成项目后进行肺功能测试,并使用WHODAS 2.0评估残疾水平。

结果

观察到肺功能有所改善,用力肺活量(FVC)和一秒用力呼气容积(FEV1)显著增加(FVC:从2.50±0.43升增加到2.85±0.59升;FEV1:从1.53±0.33升增加到1.63±0.34升;P<0.001)。WHODAS 2.0评分显示残疾状况显著降低,特别是在生活活动和参与领域(P<0.001)。认知和自我护理评分保持稳定,虽然观察到活动能力有所改善但不显著。回归分析显示FVC增加与WHODAS 2.0总分降低之间存在强烈的负相关(r=-0.65),突出了FVC作为残疾降低的关键预测指标。

结论

为期12周的居家PR项目改善了COPD患者的肺功能并降低了残疾程度。这些发现支持了居家PR作为一种可行的、以患者为中心的传统康复替代方案的作用,解决了健康的身体和社会层面问题。未来的研究应关注长期结果、更广泛实施的潜力以及扩大对服务不足人群的可及性。

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Long-term evaluation of home-based pulmonary rehabilitation in patients with COPD.慢性阻塞性肺疾病患者居家肺康复的长期评估
Int J Chron Obstruct Pulmon Dis. 2015 Sep 25;10:2037-44. doi: 10.2147/COPD.S90534. eCollection 2015.

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