Feldman Zach M, Leya Gregory, Oseran Andrew, Zheng Xinyan, Mao Jialin, Sumpio Brandon J, Srivastava Sunita D, Goodney Philip P, Conrad Mark F, Mohapatra Abhisekh
Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA.
Department of Surgery, Massachusetts General Hospital, Boston, MA.
J Vasc Surg. 2025 Apr 28. doi: 10.1016/j.jvs.2025.04.032.
Centralized aortic hubs frequently exist in competitive markets, which have at times demonstrated inferior surgical outcomes. Here we evaluate the impact of local market competition specifically on complex aortic surgical outcomes.
A retrospective review included all Vascular Quality Initiative (VQI) patients between 2013 and 2022 undergoing index complex endovascular aortic repair, thoracic endovascular aortic repair, or open aortic repair. Market competition was defined by the Herfindahl-Hirschman index (HHI), using surgeon-level market share within blinded VQI regions or metropolitan statistical areas (MSAs). A higher HHI indicates lower competition. Multivariable logistic 30-day mortality models and Cox survival models were used to examine the association between HHI and outcomes. A sensitivity analysis further adjusted for complexity among all complex and routine aortic surgical patients in the Vascular Implant Surveillance and Interventional Outcomes Network from 2017 to 2019, using generalized estimating equations with MSA-level clustering.
The VQI contained 10,868 complex aortic surgical patients, with 4372 additional patients in MSA-based Vascular Implant Surveillance and Interventional Outcomes Network sensitivity analysis. The median patient age was 75 years. Of these patients, 68.4% were male, with a greater number of patients in high competition regions (51.3%) and MSAs (34.6%) vs medium and low competition locales. Comorbidities and aneurysm diameter were broadly similar across HHI intervals. Lower 30-day mortality was observed in high competition regions (high, 23.7%; medium, 25.9%; low, 25.9%; P = .03). In multivariable logistic models, medium regional competition was associated with greater 30-day mortality odds vs high competition (odds ratio [OR], 1.39; 95% CI, 1.21-1.60; P < .001), with a trend toward increased mortality for low competition (OR, 1.20; 95% CI, 0.98-1.45; P = .07). MSA-based sensitivity analyses demonstrated a similar trend for medium competition MSAs (OR, 1.25; 95% CI, 0.98-1.58; P = .07), without significant relationship for low-competition MSAs. Regional interval was not associated with any long-term mortality difference.
More competitive regions demonstrate lower 30-day mortality after complex aortic surgery but equivalent long-term survival. Further efforts should focus on drivers of this difference to widen access to high-quality complex aortic care.
集中式主动脉治疗中心常在竞争激烈的市场中存在,而这些市场有时已显示出较差的手术结果。在此,我们评估当地市场竞争对复杂主动脉手术结果的具体影响。
一项回顾性研究纳入了2013年至2022年间接受初次复杂血管腔内主动脉修复术、胸主动脉腔内修复术或开放性主动脉修复术的所有血管质量倡议(VQI)患者。市场竞争由赫芬达尔-赫希曼指数(HHI)定义,使用VQI盲区内或大都市统计区(MSA)内外科医生层面的市场份额。HHI越高表明竞争越低。使用多变量逻辑回归30天死亡率模型和Cox生存模型来检验HHI与结果之间的关联。一项敏感性分析进一步对2017年至2019年血管植入监测与介入结果网络中所有复杂和常规主动脉手术患者的复杂性进行了调整,使用具有MSA层面聚类的广义估计方程。
VQI包含10868例复杂主动脉手术患者,在基于MSA的血管植入监测与介入结果网络敏感性分析中又有4372例患者。患者中位年龄为75岁。在这些患者中,68.4%为男性,高竞争地区(51.3%)和MSA(34.6%)的患者数量多于中等和低竞争地区。不同HHI区间的合并症和动脉瘤直径大致相似。在高竞争地区观察到较低的30天死亡率(高竞争地区为23.7%;中等竞争地区为25.9%;低竞争地区为25.9%;P = 0.03)。在多变量逻辑回归模型中,中等区域竞争与30天死亡几率高于高竞争地区相关(优势比[OR],1.39;95%可信区间[CI],1.21 - 1.60;P < 0.001),低竞争地区有死亡率增加的趋势(OR,1.20;95% CI,0.98 - 1.45;P = 0.07)。基于MSA的敏感性分析显示中等竞争MSA有类似趋势(OR,1.25;95% CI,0.98 - 1.58;P = 0.07),低竞争MSA无显著关联。区域区间与任何长期死亡率差异均无关联。
竞争更激烈的地区在复杂主动脉手术后显示出较低的30天死亡率,但长期生存率相当。应进一步努力关注造成这种差异的驱动因素,以扩大获得高质量复杂主动脉治疗的机会。